ID A0A2Z2P178_9GAMM Unreviewed; 1083 AA.
AC A0A2Z2P178;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=IMCC3135_16060 {ECO:0000313|EMBL:ASJ73294.1};
OS Granulosicoccus antarcticus IMCC3135.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Granulosicoccaceae; Granulosicoccus.
OX NCBI_TaxID=1192854 {ECO:0000313|EMBL:ASJ73294.1, ECO:0000313|Proteomes:UP000250079};
RN [1] {ECO:0000313|EMBL:ASJ73294.1, ECO:0000313|Proteomes:UP000250079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC3135 {ECO:0000313|EMBL:ASJ73294.1,
RC ECO:0000313|Proteomes:UP000250079};
RA Song W.-J., Kurnit D.M.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP018632; ASJ73294.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z2P178; -.
DR KEGG; gai:IMCC3135_16060; -.
DR OrthoDB; 9770473at2; -.
DR Proteomes; UP000250079; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 3.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 3.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000250079};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 332..402
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 448..502
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 522..572
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 573..643
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 646..699
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 719..944
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 966..1082
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 683..710
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1017
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1083 AA; 121454 MW; 0D605BF6405CF0D1 CRC64;
MTQLTVSLKE LPLRKFLQVA PDTLLSEAAR QMDNDGLDTA LVMQGQNLLG ILGSRDRLRA
FHQQTPPNTP VRELMNSAHC SLKQNTFITD ACSHLLQHAA SELVITNELG MPLGLIGESE
LLQYITPFLT NDTQANKDWV LQHASKRMEA DKQLHTLKRQ TDLLSRFAAA LINLPADDID
PVVNHALMEM GELVQVDRAY IFHYDFDTDT ACNTHEWCAS GISPQIHNLQ VLPIQELSDW
VCKHKRSENV VVDDFNLLPP GMMREVMEQQ DIKSMVCLPI LGNEGCIGFL GFDSVRSKRQ
YAPEDLEVLE LFARTLANYR ERLIAEQKLA NNEANFHAFF DQTQDLLFVL SQQGDIVQCN
TQATQRLGFS MEELYGKPVL QLHPDENHTE AAQIVADMAK GKTDCHAIPM QTRFGQQVPM
ETRVVAGQWN GIPALFMVCR DLSDITSSEE KFSKAFHLSP MPMAISDVQN GTFLEVNEAF
FHVTGYDTHE VVGKNVAAMN LFGDLKLWGH IIEQLQQQGQ VNNIEFPLRT KQGDIVYGLL
SAALLELQGR QVMISQLLDI TARKTAEEAL VNERLLLRTL INSQLNLVWL KDPEGAYLAC
NSRFESLYGH TESEILGRTD IEFVNQEWAE FFRKNDHLAI KAGKPRINEE TLTFASNGYQ
GLFETTKTPI FNGQQKLLGV LGVAREITHA RHAEQERRRM ERELHQSRKM EALGQLTGGV
AHEFNNMLAI ILGYKDLLQA KLDPSTDSSI NIWLDHIDVA GVRAKELVRQ LLSFSRPNEK
QPKRINLEIG VRKAIALSQS SLPSSIEIDY RPDPELPDVQ LDIGELQQML TNVLVNARDA
MDGKGRIEVT LQHTRHTEQE CQLCHTLIEG YWVELCIADD GPGIFPEQLS RIFEPFYTTK
AVGKGTGLGL SLVHSIMEHN GGHILLDSRP GEGTRFCLLF RPLDDEALKS IPMHTPVETP
SLKAGRVLVV DDEPALTEFL KETLELQGLQ VIALNDSREA LDLLLEPEQQ FDLLITDQTM
PGMLGTELAT QAKNHLGDLK VILCTGHSEQ INADNAAEFG IDSFLKKPIG IQDIVIAIDN
LSK
//
