ID A0A2Z4FIM3_9DELT Unreviewed; 340 AA.
AC A0A2Z4FIM3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA polymerase III subunit delta' {ECO:0000256|ARBA:ARBA00014363};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=holB {ECO:0000313|EMBL:AWV88782.1};
GN ORFNames=DFR33_11619 {ECO:0000313|EMBL:TDP61780.1}, DN745_05285
GN {ECO:0000313|EMBL:AWV88782.1};
OS Bradymonas sediminis.
OC Bacteria; Deltaproteobacteria; Bradymonadales; Bradymonadaceae; Bradymonas.
OX NCBI_TaxID=1548548 {ECO:0000313|EMBL:AWV88782.1, ECO:0000313|Proteomes:UP000249799};
RN [1] {ECO:0000313|EMBL:AWV88782.1, ECO:0000313|Proteomes:UP000249799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FA350 {ECO:0000313|EMBL:AWV88782.1,
RC ECO:0000313|Proteomes:UP000249799};
RA Guo L.-Y., Li C.-M., Wang S., Du Z.-J.;
RT "Lujinxingia sediminis gen. nov. sp. nov., a new facultative anaerobic
RT member of the class Deltaproteobacteria, and proposal of Lujinxingaceae
RT fam. nov.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TDP61780.1, ECO:0000313|Proteomes:UP000294609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 28820 {ECO:0000313|EMBL:TDP61780.1,
RC ECO:0000313|Proteomes:UP000294609};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; CP030032; AWV88782.1; -; Genomic_DNA.
DR EMBL; SNXT01000016; TDP61780.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z4FIM3; -.
DR KEGG; bsed:DN745_05285; -.
DR OrthoDB; 9810148at2; -.
DR Proteomes; UP000249799; Chromosome.
DR Proteomes; UP000294609; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR015199; DNA_pol_III_delta_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF09115; DNApol3-delta_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:AWV88782.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000249799};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AWV88782.1}.
FT DOMAIN 222..335
FT /note="DNA polymerase III delta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09115"
SQ SEQUENCE 340 AA; 38355 MW; 68F52009C6B665CC CRC64;
MLKWSKIRGQ ARPLEILSTA LDADRVHHAY LFTGMEGVGK FLTAQTLSAV VNCERRPEGA
FQDACGACRS CRKIVDWKHP DILPVRPTKG TIKIGQIRDI QKASNRAPYE ARVRFVLIDD
AHTMTDEAAN ALLKTLEEPA QRMRLILVTD QPHRLLETIL SRCQAIRFDR LDEALVTELL
REILAEKQEE DALEDLTDLS VAAGYGEGSL GRSLAVIESG MLKGRKDFIG KVVNLSAGQP
VALLDLAEDL KSSRDEMTSR LDVLMLFFRD VMLYKAAEDS TRLVNSDLRM QIQALSERME
MEDILDIIDE IRQAQRYLLA NVNSQLIAEE LLGQIRRRRA
//
