ID A0A2Z4L7V9_9EURY Unreviewed; 222 AA.
AC A0A2Z4L7V9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Translation initiation factor 6 {ECO:0000256|HAMAP-Rule:MF_00032};
DE Short=aIF-6 {ECO:0000256|HAMAP-Rule:MF_00032};
GN Name=eif6 {ECO:0000256|HAMAP-Rule:MF_00032};
GN ORFNames=AW729_04360 {ECO:0000313|EMBL:AWX32381.1};
OS Methanosphaera sp. BMS.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX NCBI_TaxID=1789762 {ECO:0000313|EMBL:AWX32381.1, ECO:0000313|Proteomes:UP000249370};
RN [1] {ECO:0000313|Proteomes:UP000249370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BMS {ECO:0000313|Proteomes:UP000249370};
RA O Cuiv P.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AWX32381.1, ECO:0000313|Proteomes:UP000249370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BMS {ECO:0000313|EMBL:AWX32381.1,
RC ECO:0000313|Proteomes:UP000249370};
RA Morrison M.;
RT "Methanosphaera spp. pan-genomic study of isolate and population genomes.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Binds to the 50S ribosomal subunit and prevents its
CC association with the 30S ribosomal subunit to form the 70S initiation
CC complex. {ECO:0000256|HAMAP-Rule:MF_00032}.
CC -!- SIMILARITY: Belongs to the eIF-6 family. {ECO:0000256|HAMAP-
CC Rule:MF_00032}.
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DR EMBL; CP014213; AWX32381.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z4L7V9; -.
DR KEGG; metb:AW729_04360; -.
DR OrthoDB; 33582at2157; -.
DR Proteomes; UP000249370; Chromosome.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0042256; P:cytosolic ribosome assembly; IEA:InterPro.
DR HAMAP; MF_00032; eIF_6; 1.
DR InterPro; IPR002769; eIF6.
DR NCBIfam; TIGR00323; eIF-6; 1.
DR PANTHER; PTHR10784; EUKARYOTIC TRANSLATION INITIATION FACTOR 6; 1.
DR PANTHER; PTHR10784:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 6; 1.
DR Pfam; PF01912; eIF-6; 1.
DR PIRSF; PIRSF006413; IF-6; 1.
DR SMART; SM00654; eIF6; 1.
DR SUPFAM; SSF55909; Pentein; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540, ECO:0000256|HAMAP-
KW Rule:MF_00032};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|HAMAP-
KW Rule:MF_00032}.
SQ SEQUENCE 222 AA; 23564 MW; 31C7E31041EC1F8C CRC64;
MIQRFDIDGN PNLGVSILAK DNVAIVSPGL QDSYTKSIEE TLKVPIIKTP ICGSNLAGAL
MAGNSNGLIV SPHIFSHELD IIREHDINVE IMPDKLTAIG NIVVANDNGA IVHPDLSKES
RRIIRKTLEV EVTEATIAGF DIVGSAIAAT NRGALVHPDA TDEELELVED ALGVTTKIGT
VNRGVKLVGA CIIANSNGVI VGNKTTGPEL ARIDQVFNLF EE
//
