ID A0A2Z4UZS8_9ACTN Unreviewed; 333 AA.
AC A0A2Z4UZS8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000256|HAMAP-Rule:MF_01420,
GN ECO:0000313|EMBL:AWZ14241.1};
GN ORFNames=DRB96_20440 {ECO:0000313|EMBL:AWZ14241.1};
OS Streptomyces sp. ICC1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2099583 {ECO:0000313|EMBL:AWZ14241.1, ECO:0000313|Proteomes:UP000250268};
RN [1] {ECO:0000313|EMBL:AWZ14241.1, ECO:0000313|Proteomes:UP000250268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICC1 {ECO:0000313|EMBL:AWZ14241.1,
RC ECO:0000313|Proteomes:UP000250268};
RA Gosse J.;
RT "Whole genome sequencing and metabolomic study of cave Streptomyces
RT isolates ICC1 and ICC4.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000256|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000256|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; CP030287; AWZ14241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z4UZS8; -.
DR Proteomes; UP000250268; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR NCBIfam; TIGR00647; DNA_bind_WhiA; 1.
DR PANTHER; PTHR37307; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR PANTHER; PTHR37307:SF1; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01420}; Reference proteome {ECO:0000313|Proteomes:UP000250268}.
FT DOMAIN 19..104
FT /note="Sporulation transcription regulator WhiA N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10298"
FT DOMAIN 127..218
FT /note="WhiA LAGLIDADG-like"
FT /evidence="ECO:0000259|Pfam:PF14527"
FT DOMAIN 221..303
FT /note="Sporulation regulator WhiA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02650"
FT REGION 311..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 333 AA; 35457 MW; 47873D6FA18F1A9E CRC64;
MAMTPAVKDE IARLPVTRTC CRKAEVSAIL RFAGGLHLVS GRIVIEAELD AGIAARRLRK
DILEIFGHSS DLVIMAPGGL RRGNRYVVRV VAGGDQLARQ TGLVDGRGRP IRGLPPQVVS
GATCDAEAAW RGAFLAHGSL TEPGRSSSLE VTCPGPEAAL ALVGAARRLS IAAKAREVRG
VDRVVVRDGD AIGALLTRLG AHDSVLAWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAGARVQRAL EILAEEVPEH LAAAGRLRME HKQASLEELG ALADPPLTKD AVAGRIRRLL
AMADKRAQDL GIPGTESNLD LSDSEELADN MAG
//
