ID A0A2Z5R318_9MICC Unreviewed; 191 AA.
AC A0A2Z5R318;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Aspartate-semialdehyde dehydrogenase {ECO:0000313|EMBL:BAV88944.1};
GN ORFNames=RA11412_2645 {ECO:0000313|EMBL:BAV88944.1};
OS Rothia aeria.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Rothia.
OX NCBI_TaxID=172042 {ECO:0000313|EMBL:BAV88944.1, ECO:0000313|Proteomes:UP000250241};
RN [1] {ECO:0000313|EMBL:BAV88944.1, ECO:0000313|Proteomes:UP000250241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 11412 {ECO:0000313|EMBL:BAV88944.1,
RC ECO:0000313|Proteomes:UP000250241};
RA Nambu T.;
RT "Genome sequence of Rothia aeria strain JCM11412.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aspartate-semialdehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00010584}.
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DR EMBL; AP017895; BAV88944.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z5R318; -.
DR KEGG; raj:RA11412_2645; -.
DR Proteomes; UP000250241; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR InterPro; IPR012280; Semialdhyde_DH_dimer_dom.
DR PANTHER; PTHR46278:SF4; ASPARTATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR46278; DEHYDROGENASE, PUTATIVE-RELATED; 1.
DR Pfam; PF01118; Semialdhyde_dh; 1.
DR Pfam; PF02774; Semialdhyde_dhC; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000250241}.
FT DOMAIN 2..51
FT /note="Semialdehyde dehydrogenase NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01118"
FT DOMAIN 75..182
FT /note="Semialdehyde dehydrogenase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF02774"
SQ SEQUENCE 191 AA; 20795 MW; 68BB366FA1522244 CRC64;
MTAQGGDYTK EVHPKLRESG WEGLWIDAAS ALRMNDDAII VLDPINRDVI DRGLESGVKD
FIGGNCTVSC LLMGLGGLFK QGLVEWTTSM TYQAASGGGA RHMREVLGQF RDLGNEVSAE
LNDPAAAILE IDRKVLAKQR SGELDTAQFG VPLSGSLIPW IDSDLGNGQS REEWKSDAET
NKFWVLRAIT V
//
