ID   A0A2Z6GE27_9PROT        Unreviewed;      1040 AA.
AC   A0A2Z6GE27;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE            EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN   ORFNames=OYT1_ch2356 {ECO:0000313|EMBL:BBE51871.1};
OS   Ferriphaselus amnicola.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Gallionellaceae; Ferriphaselus.
OX   NCBI_TaxID=1188319 {ECO:0000313|EMBL:BBE51871.1, ECO:0000313|Proteomes:UP000033070};
RN   [1] {ECO:0000313|EMBL:BBE51871.1, ECO:0000313|Proteomes:UP000033070}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OYT1 {ECO:0000313|EMBL:BBE51871.1,
RC   ECO:0000313|Proteomes:UP000033070};
RA   Kato S., Itoh T., Ohkuma M.;
RT   "OYT1 Genome Sequencing.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC         fragments with terminal 5'-phosphates, ATP is simultaneously
CC         hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC   -!- SIMILARITY: Belongs to the HsdR family.
CC       {ECO:0000256|ARBA:ARBA00008598}.
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DR   EMBL; AP018738; BBE51871.1; -; Genomic_DNA.
DR   RefSeq; WP_062626684.1; NZ_AP018738.1.
DR   AlphaFoldDB; A0A2Z6GE27; -.
DR   STRING; 1188319.OYT1_01507; -.
DR   REBASE; 253825; FamOYT1ORF2360P.
DR   KEGG; fam:OYT1_ch2356; -.
DR   OrthoDB; 9758243at2; -.
DR   Proteomes; UP000033070; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1570.50; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR   InterPro; IPR040980; SWI2_SNF2.
DR   PANTHER; PTHR42927; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR42927:SF1; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF04313; HSDR_N; 1.
DR   Pfam; PF18766; SWI2_SNF2; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033070};
KW   Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT   DOMAIN          275..511
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|SMART:SM00487"
SQ   SEQUENCE   1040 AA;  115720 MW;  B2DE7BA7E2B2AB81 CRC64;
     MTGLHKEIEF ENDICEHLAA HDWLYAEGDF TAYDRARAVF PADVIAWVQA TQPKAWESLS
     KSHGAATETV LLDRIRKQLD DRGTLDVLRH GIELLGLRQP LQLAQFKPAL AMNSELQAKY
     AANRLRVVRQ VRYSLFNENA IDLVLFLNGL PIATVELKSH FTQSVDDAVD QYRFDRHPKP
     KGQAAAEPLL DFPRGALVHF AVSNSAAMMT TRLLGAATTF LPFNLGDHGA AGNPVNPNGH
     RTAYLWEQVW ARESWLEIIG RYIVAKRDSK KQIKAIIFPR YHQLDATRKL VAAVISEGAG
     QKYLIQHSAG SGKTNSIAWT AHFLADLHDA QHKKLFDSVL VVSDRTVLDT QLQEAIFDFE
     RTAGVVATIK GESQSKSGEL AQALSGGKKI VVCTIQTFPF ALQAVRELAA TQGKRFAVIA
     DEAHSSQTGT AASKLKQLLS AEEMQELADG GEVGTEDLLA MQMAARSNDA GITYVAFTAT
     PKAKTLELFG RRPNPALPAS DENLPAPFHV YSMRQAIEEG FILDVLKNYT PYKLAFKLAN
     EGHEWDEKEV ERSTAMKGIM RWVRLHPYNI SQKVQVVVEH FRDSVQPLLE GKAKAMVVVG
     SRLEAVRWQI AIDKYIKSQG YKIGTLVAFS GEVNDQESHP DPLTETSKVL NTNLNGRDIR
     EAFATDEYQI LLVANKFQTG FDQPLLCGMY VDKRLAGIQA VQTLSRLNRA YPGKDTTYIL
     DFVNDPNEVL AAFKTYYETA ELDGVTDPNL VYDLRAKLDA EGHYDDNEVD RVVNVEMNPH
     ASQAELSAAI EPVADRLLKR YRAALTNHQA AVANKDAKAE QEAQDEMNAL MLFKRNLGAF
     QRVYAFLSQI FDYGNTAIEK RAIFFKRLLP LLEFGREREG VDLSKVTLTH HKLKDQGKRN
     LALVNGEYPK LSPLSETGSG EVQQKEKVYL AEIITKVNEL FEGELTDDDK LIYVNHVLKG
     KLLESEILVQ QANNNTKEQF ANSPDLSNAI LSAIMDALSA HSTLSKQALD SEKVRSGLKD
     VLLGPAQLYE ALRAQQVVNG
//