ID A0A2Z6QPC9_9GLOM Unreviewed; 1498 AA.
AC A0A2Z6QPC9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Eukaryotic translation initiation factor 5B {ECO:0000256|ARBA:ARBA00013824};
DE AltName: Full=Translation initiation factor IF-2 {ECO:0000256|ARBA:ARBA00032478};
GN ORFNames=RclHR1_18700002 {ECO:0000313|EMBL:GBB91425.1};
OS Rhizophagus clarus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX NCBI_TaxID=94130 {ECO:0000313|EMBL:GBB91425.1, ECO:0000313|Proteomes:UP000247702};
RN [1] {ECO:0000313|EMBL:GBB91425.1, ECO:0000313|Proteomes:UP000247702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HR1 {ECO:0000313|EMBL:GBB91425.1,
RC ECO:0000313|Proteomes:UP000247702};
RA Kobayashi Y.;
RT "The genome of Rhizophagus clarus HR1 reveals common genetic basis of
RT auxotrophy among arbuscular mycorrhizal fungi.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBB91425.1}.
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DR EMBL; BEXD01000969; GBB91425.1; -; Genomic_DNA.
DR STRING; 94130.A0A2Z6QPC9; -.
DR Proteomes; UP000247702; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0030908; P:protein splicing; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
DR CDD; cd03703; aeIF5B_II; 1.
DR CDD; cd01887; IF2_eIF5B; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR029459; EFTU-type.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR007868; Hom_end_hint.
DR InterPro; IPR007869; Homing_endonuc_PI-Sce.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF14578; GTP_EFTU_D4; 1.
DR Pfam; PF05204; Hom_end; 1.
DR Pfam; PF05203; Hom_end_hint; 1.
DR Pfam; PF11987; IF-2; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000247702}.
FT DOMAIN 897..1115
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..477
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1498 AA; 169208 MW; 65504E5DC6ACAF4E CRC64;
MTQISKASKK NKKKKNKNAV TDDDYADSQI LGEEGASSEA IPVVLTEVQA VQPDDWAEEE
FGVSNNKDKK KKKGGKDNKT ESLVKNDESI EKEKQNEDSG EIRILSKKEK EKLKKQRDKE
KKKSEAEKKK AQKTDEVVKQ EEIKEVKEEP KSIPSEEPPE VADEENEEDG TKSKSKKKKK
KKPAEEEKKP AGKKKPQVAA IRKLLEAQRA EEEARKREEE ELQKKLEEER KRIEEEERLK
EEAKRKKKEK EKAKKEQLKK EGKLLTKAQK TKKQQDQLRL QQMVEAGHLK IEGLSQDSEQ
KPKKIVYSSK KKPPNKQRMG QIEAERSATE VKDSIEPMKE KVEIKEEKES EEQGAETEEV
DISKKVKASW EDSEDEIQNK EEKETVKDQW DESTEDEAPS PKAKIPQSIP DKKQEPVKKV
DKTTTKVDKT TTKVKPSVET PVKKSAKKEE SEEESEEGSE ETETGSEDDS EDDSESEEEL
TEHKKQQLKR KQEAAERRKK RHEEALANRS KDNLRSPICC ILGHVDTGKC FGKGTPILMY
DGSVRAVETI QAGDQVMGDD STPRNVSGVT SGKGLLYKII PINNSSAQPF VCNDAHILVL
KITSSPYIQH QKRKGQFCLN YFIYDKKTNL VEKANRFYKY PTSQFQTKYH AKKAAIKDLE
MINSEKNPNL SINSNADFEI VRRDFIWQPS VTQFLNCSSE IRSASNMFTP NRVRFSIREG
TFAKIIERII GSPITNNIIK FYSWLTGYWI GTNFVMSNTK FENENQDIVV SLFDELGILQ
RKDIPEIMMY EDIDLVRLPF LAGMIDSTGL YNSQDDVTEV TLMNDYNVKN FVKISRSCGL
RVSVSDPQNR CIVHKASIIS SVLSRSNCKI NDHKHDQLWG FQIKELGVGE YFGFVVDGNH
RFLLGDFTVT HNTKLLDKIR QTNVQEGEAG GITQQIGATY FPMETIKTKT APLNKDGKQE
YKLPGLLIID TPGHESFTNL RSRGSSLCNI AILVVDIMHG LEPQTLESLR LLRDRKTPFI
VALNKIDRMY GWKSIPDNSF IDSLSKQSEN VQREFKDRVD KTILAFSEQG LNSVLYYENK
NFAKNVSLVP TSAITGEGIP DMLMLLVNLT QSRMSDALMY LSELECTVLE VKVIEGLGTT
IDVILSNGVL NEGEKIVLCG LNGPIVTTVR ALLTPQPLKE LRVKSAYVHH KSVKAALGVK
ISAQDLEKAI AGSRLMVVGP DDDEDDLKDE VMSDLKSLLS SIDKSGKGVC VQASTLGSLE
ALLEFLRTSK IPVSGINIGP VHKKDIMRAS TMLERAKEFA VILCFDVKVD KEAQDLAEEL
GIKIFKADII YHLFDQFVAY NKEIVEQKRK DQAPQAVFPC ILKIVPGAIF NKKDPIIIGV
DVVDGVLRTG TPLCVVKIDP ITNQREIISL GKVSSMEQNH KTIEVAKKGN TGAGIAIKIE
CAVYESSKTF GRHFIETDEI YSKISRVSID VLKESFRNDL SKEEWALVIK LKKILEIN
//
