ID A0A2Z6QQN0_9GLOM Unreviewed; 788 AA.
AC A0A2Z6QQN0;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Vacuolar protein sorting-associated protein 51 homolog {ECO:0000256|RuleBase:RU368010};
GN ORFNames=RclHR1_00200030 {ECO:0000313|EMBL:GBB92397.1};
OS Rhizophagus clarus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX NCBI_TaxID=94130 {ECO:0000313|EMBL:GBB92397.1, ECO:0000313|Proteomes:UP000247702};
RN [1] {ECO:0000313|EMBL:GBB92397.1, ECO:0000313|Proteomes:UP000247702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HR1 {ECO:0000313|EMBL:GBB92397.1,
RC ECO:0000313|Proteomes:UP000247702};
RA Kobayashi Y.;
RT "The genome of Rhizophagus clarus HR1 reveals common genetic basis of
RT auxotrophy among arbuscular mycorrhizal fungi.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as component of the GARP complex that is involved in
CC retrograde transport from early and late endosomes to the trans-Golgi
CC network (TGN). {ECO:0000256|RuleBase:RU368010}.
CC -!- SUBUNIT: Component of the Golgi-associated retrograde protein (GARP)
CC complex. {ECO:0000256|RuleBase:RU368010}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC {ECO:0000256|RuleBase:RU368010}.
CC -!- SIMILARITY: Belongs to the VPS51 family.
CC {ECO:0000256|ARBA:ARBA00006080, ECO:0000256|RuleBase:RU368010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBB92397.1}.
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DR EMBL; BEXD01001113; GBB92397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z6QQN0; -.
DR STRING; 94130.A0A2Z6QQN0; -.
DR Proteomes; UP000247702; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0000938; C:GARP complex; IEA:UniProtKB-UniRule.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007030; P:Golgi organization; IEA:UniProtKB-UniRule.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:UniProtKB-UniRule.
DR InterPro; IPR039481; EXOC2/Sec5_N_dom.
DR InterPro; IPR014812; Vps51.
DR PANTHER; PTHR15954; UNCHARACTERIZED; 1.
DR PANTHER; PTHR15954:SF4; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG; 1.
DR Pfam; PF15469; Sec5; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|RuleBase:RU368010};
KW Lipid transport {ECO:0000256|RuleBase:RU368010};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|RuleBase:RU368010};
KW Reference proteome {ECO:0000313|Proteomes:UP000247702};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU368010}.
FT TRANSMEM 690..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..215
FT /note="Exocyst complex component EXOC2/Sec5 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15469"
FT REGION 159..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 788 AA; 89682 MW; 2F1D1B658BF6F4A3 CRC64;
MDQLSQSINN ISNVASSANS ALGLKRDKIR QLTGVHDLLK KIQFIFELPT RLKNCLDQES
YVQAVRYYAK TSKLLEHYRS LSVFSSIETE CKEIMDKVTK RIRENMTNIK ATGSEITDCM
ALLIILKEPP QQLAKEYLEL QKNFLMNLLR KTIEEMSSLS VDSSQDNQPN NANSEHRKEP
SSPISQKKRA KSKLTFLNQK FLKELNKFVE SFNGFFLTPP REIREAKSPG KSPGKSPRSA
GSDILRIVSA NMDGDDKDIA RQEFSNFVDD IAKLYFFAVD SLLEFPERIT NLNPSTHLHL
LNDLYYATLS CNSLCTIARF EDRVNEVITA WEIKFAKSLF ETAEKKMMEN FTKYAEKELE
KGSSTSANSQ IHELQSYILD MEASFTDYLT GDCLRLLEEC IKTETPMVQK KGGVDRLLKG
FQTQFKEFWR SIVHSSSKYV APVHPTPTTQ KLVPPPPPII ALIMSRVLLD FGEIIVIQVY
MAFSNILYKQ QSDYRNRIGV EIYNGLGEKY TIAKELAHDV REVVGICKDV AQRVLERYVE
IKGDQVSSKI RDIYIPNYIQ KFDENLGKSP LPEKVTPIWS EIITDLVYIE REVVMLYGGP
VDEEGSKEVG NLVEKRLNPF LQPGTSSNAG GGDKSLLSPG TALVKSPYAH SNSSYSSISS
TRSRTSPNPF TSSVQLTSHI DKLFSDRIEI YGIVEMSIIG IMMGIIKILL KTWIEMIRLN
TLTNKSFRQL QVDSEYMRVK LWRFIEDERI MNTMLQELAS SAFKRCIEDP LPLVYADIEM
IVNGTVSY
//
