ID   A0A2Z6QQT6_9GLOM        Unreviewed;       676 AA.
AC   A0A2Z6QQT6;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=Prolyl endopeptidase {ECO:0000256|RuleBase:RU368024};
DE            EC=3.4.21.- {ECO:0000256|RuleBase:RU368024};
GN   ORFNames=RCL2_002843000 {ECO:0000313|EMBL:GET02049.1}, RclHR1_01380006
GN   {ECO:0000313|EMBL:GBB87344.1};
OS   Rhizophagus clarus.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC   Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX   NCBI_TaxID=94130 {ECO:0000313|EMBL:GBB87344.1, ECO:0000313|Proteomes:UP000247702};
RN   [1] {ECO:0000313|EMBL:GBB87344.1, ECO:0000313|Proteomes:UP000247702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HR1 {ECO:0000313|EMBL:GBB87344.1,
RC   ECO:0000313|Proteomes:UP000247702};
RA   Kobayashi Y.;
RT   "The genome of Rhizophagus clarus HR1 reveals common genetic basis of
RT   auxotrophy among arbuscular mycorrhizal fungi.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:GET02049.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HR1 {ECO:0000313|EMBL:GET02049.1};
RA   Maeda T., Kobayashi Y., Nakagawa T., Ezawa T., Yamaguchi K., Bino T.,
RA   Nishimoto Y., Shigenobu S., Kawaguchi M.;
RT   "Conservation and host-specific expression of non-tandemly repeated
RT   heterogenous ribosome RNA gene in arbuscular mycorrhizal fungi.";
RL   Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of Pro-|-Xaa >> Ala-|-Xaa in oligopeptides.;
CC         EC=3.4.21.26; Evidence={ECO:0000256|ARBA:ARBA00001070};
CC   -!- SIMILARITY: Belongs to the peptidase S9A family.
CC       {ECO:0000256|ARBA:ARBA00005228, ECO:0000256|RuleBase:RU368024}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBB87344.1}.
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DR   EMBL; BEXD01000424; GBB87344.1; -; Genomic_DNA.
DR   EMBL; BLAL01000304; GET02049.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2Z6QQT6; -.
DR   Proteomes; UP000247702; Unassembled WGS sequence.
DR   Proteomes; UP000615446; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   Gene3D; 2.130.10.120; Prolyl oligopeptidase, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR023302; Pept_S9A_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   PANTHER; PTHR42881; PROLYL ENDOPEPTIDASE; 1.
DR   PANTHER; PTHR42881:SF2; PROLYL ENDOPEPTIDASE; 1.
DR   Pfam; PF00326; Peptidase_S9; 2.
DR   Pfam; PF02897; Peptidase_S9_N; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU368024};
KW   Protease {ECO:0000256|RuleBase:RU368024};
KW   Reference proteome {ECO:0000313|Proteomes:UP000247702};
KW   Serine protease {ECO:0000256|RuleBase:RU368024}.
FT   DOMAIN          6..424
FT                   /note="Peptidase S9A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02897"
FT   DOMAIN          490..525
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
FT   DOMAIN          535..661
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
SQ   SEQUENCE   676 AA;  78963 MW;  800293043241D09E CRC64;
     MAWEYPKVRR DENFFENLHG YEVADPYRWL EDPKSEETMT FVDDQNALAS KYLDSCPYRE
     KYRESLTKIF DHEKYDCPKK HGDNYYYFYN SGLQPQSVLY QLKGSLNAQP EEFFNPNNLE
     ADGTASLNIH SFSKNGNYFS YGISKSGSDW VTVYVRKTIN DEEGKKPLPD VIEWVKFSDL
     SWTIDEKGFF YNRYPEQNDN NDRGTETDNN MNAMLYYHRI GTFQSEDILV YKDPENPEYK
     FKAQCTLDGQ FVVISIKKDC NPNKLYLIDL KKTNYQINEN NDIIRIVDNF DARYYYLAND
     DSTFYFMTNA NAPRYRIVKY DLSNREQGFV DVVKEHPTDV LLDAAVLAEN KLVLTYMHDV
     KHKMYIHEYS TGKFLKEIPL DIGSVVTLSG RREDYECFFK FVSFLNPGIM YHYDFKNDLL
     TEYRKTKVNG LNCDKMETDQ FFAESKDKIK IPAFIIKPKN INFDGNNPTF LYGYGGFNHS
     LSPVFSLNFL SFIRHFNGIV VFANIRGGGE YGEEWHKAGC FSNKQMFLMI FWLLLNGACI
     NQAPELFGAA VPNVGVMDML RFHKFTIGHA WKSDYGDPDK KEDFEYIYKY SPYHNVQTNK
     VYPATLLLTS DHDDRVVPLH SYKYISQLQY VAKNNPYPLM IKIHQKAGHG AGRPTQKIID
     EAIDRFTMSI GAKWND
//