ID   A0A2Z6RL74_9GLOM        Unreviewed;      1016 AA.
AC   A0A2Z6RL74;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=Presequence protease, mitochondrial {ECO:0000256|ARBA:ARBA00020167};
DE   AltName: Full=Pitrilysin metalloproteinase {ECO:0000256|ARBA:ARBA00034552};
GN   ORFNames=RCL2_000998200 {ECO:0000313|EMBL:GES82798.1}, RclHR1_05190010
GN   {ECO:0000313|EMBL:GBC03546.1};
OS   Rhizophagus clarus.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC   Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX   NCBI_TaxID=94130 {ECO:0000313|EMBL:GBC03546.1, ECO:0000313|Proteomes:UP000247702};
RN   [1] {ECO:0000313|EMBL:GBC03546.1, ECO:0000313|Proteomes:UP000247702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HR1 {ECO:0000313|EMBL:GBC03546.1,
RC   ECO:0000313|Proteomes:UP000247702};
RA   Kobayashi Y.;
RT   "The genome of Rhizophagus clarus HR1 reveals common genetic basis of
RT   auxotrophy among arbuscular mycorrhizal fungi.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:GES82798.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HR1 {ECO:0000313|EMBL:GES82798.1};
RA   Maeda T., Kobayashi Y., Nakagawa T., Ezawa T., Yamaguchi K., Bino T.,
RA   Nishimoto Y., Shigenobu S., Kawaguchi M.;
RT   "Conservation and host-specific expression of non-tandemly repeated
RT   heterogenous ribosome RNA gene in arbuscular mycorrhizal fungi.";
RL   Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Monomer and homodimer; homodimerization is induced by binding
CC       of the substrate. {ECO:0000256|ARBA:ARBA00011853}.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family. PreP subfamily.
CC       {ECO:0000256|ARBA:ARBA00007575}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBC03546.1}.
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DR   EMBL; BEXD01003892; GBC03546.1; -; Genomic_DNA.
DR   EMBL; BLAL01000062; GES82798.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2Z6RL74; -.
DR   STRING; 94130.A0A2Z6RL74; -.
DR   Proteomes; UP000247702; Unassembled WGS sequence.
DR   Proteomes; UP000615446; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   InterPro; IPR013578; Peptidase_M16C_assoc.
DR   PANTHER; PTHR43016; PRESEQUENCE PROTEASE; 1.
DR   PANTHER; PTHR43016:SF13; PRESEQUENCE PROTEASE, MITOCHONDRIAL; 1.
DR   Pfam; PF08367; M16C_assoc; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SMART; SM01264; M16C_associated; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000247702}.
FT   DOMAIN          503..750
FT                   /note="Peptidase M16C associated"
FT                   /evidence="ECO:0000259|SMART:SM01264"
SQ   SEQUENCE   1016 AA;  116127 MW;  39F947284FBE6989 CRC64;
     MNSLLVRRNL QKLQKVTSPH NNKLLNVICK KSYSRVVGEE FKLNDKLHGF RVEQINHIPE
     LELTATQLVH EKTGASHLHI ARDDNNNVFG VGFSTPPMNS SGTPHILEHT TLCGSKKFPV
     RDPFFKMLNR TLANFMNAMT ANDYTIYPFS TTHKLDYENL RDVYMDATFH PYLRELDFKQ
     EGWRLEHQQP NDKSSPLQFK GVVYNEMKGV MSDAGYLFYN RVQENMFLGT TYGNNSGGDP
     KHITDLTYQE LLQFHKTHYH PSNAKFYTYG NFPLSDHLAA INNKIGGFEK SDLDEGVKYV
     KPFDSSPKRI NLYGPLDPMI NSEKQAKMSI SFLTNDISNT FETFALKIFS YLLLDGHASP
     MYKALIDGNI GSDFSENTGY DSSTKISYMS IGLQGINEKY VPLAEETIKK VLEDVSQNGF
     DSKRIEAAIH QTELSIKHKT ASFGLSLMHL ISSGWFNGSN PAEYLEINNN IKLLKEKLKT
     EPFFQNLVKK YFINNPNTLI SVMTPDSSYT EKLLQEEQSR LEAKRSTLTS EDKEKIYMQS
     IELLKKQEEE EDLSVLPSLK IQDIDKQTKK FELKFTDVNK CPVQWRNTST NEITYFRIIN
     KIEGLKEDLR IYLPLFAQAL TSLGTKSKSM AVIDDDIRLY TGGINVSTFL STNHSDLNQH
     EDGLLITAHS LDRNINHMYD ILKQLLCETN FDNVDKLRTI IYANATNMMN SVVESGHQYA
     STFAGSRLIP TMSKAEIYGG MTQVHFMNKL AANEDFDTII QKLKEISEYV LSKQSLRAAI
     TCSSEAVDHN INSLSNFLNE LPEKTISRSV EQIPFQPAHE KAFFPLPFAV NFCAEAFKGV
     PYTHPDGAKL QILSSLMRAH YLHREIRERN GAYGGGATYN ASTGIFSFYS YRDPKTLETL
     KTYRDSIEWV GKRKFTQQEI DEAKLSTFKK IDEPISVSEE GMNYFTGRIT DEQRQKRREQ
     LLAVTEDDVK EVAKIYLEKQ EKESLNSIAI IGEGKPEILN DKEWKIYELS TEDEKK
//