ID   A0A2Z6S7B2_9GLOM        Unreviewed;      1170 AA.
AC   A0A2Z6S7B2;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN   ORFNames=RclHR1_06070006 {ECO:0000313|EMBL:GBC05170.1};
OS   Rhizophagus clarus.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC   Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX   NCBI_TaxID=94130 {ECO:0000313|EMBL:GBC05170.1, ECO:0000313|Proteomes:UP000247702};
RN   [1] {ECO:0000313|EMBL:GBC05170.1, ECO:0000313|Proteomes:UP000247702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HR1 {ECO:0000313|EMBL:GBC05170.1,
RC   ECO:0000313|Proteomes:UP000247702};
RA   Kobayashi Y.;
RT   "The genome of Rhizophagus clarus HR1 reveals common genetic basis of
RT   auxotrophy among arbuscular mycorrhizal fungi.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBC05170.1}.
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DR   EMBL; BEXD01003990; GBC05170.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2Z6S7B2; -.
DR   STRING; 94130.A0A2Z6S7B2; -.
DR   Proteomes; UP000247702; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR024862; TRPV.
DR   PANTHER; PTHR10582:SF2; INACTIVE; 1.
DR   PANTHER; PTHR10582; TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SUPFAM; SSF69322; Tricorn protease domain 2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000247702};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        682..708
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        805..825
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        837..855
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        867..887
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        894..916
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        922..955
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1040..1063
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          809..1073
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          18..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..34
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1170 AA;  138588 MW;  F2E084313E88ABC3 CRC64;
     MSQMDEFSVE IDDKIDNNND VHNVHNDKID VGNNKPHNGK PITKIEVSPN EKYLVTYSGE
     DNSIVGWNVD NDEDEGLLKD CHFPFNSPIQ FSLIQICVSD DKKLVYIGHE GIYDMMNYQK
     IKLDCGVYNN YAYCTFNLEG NLILYYNDVE SAIIFFYSAQ AEKTVLKCER MYKMPKNIKD
     YIFISISKYD KLYLLSNNSI YEWNIVTEKR TKLIVIDEEI KYKDTRISSN EDFVCLKIKN
     KIIIYSVELE IPIASLDINN VIQLRKFAKH PVLCFLLFPL LLPLLNDNIP SSNGYWGTIM
     RNRRKKFWSK LQISNNIKAT NKYIFGALDA DIWKIDLKEI IQNITSSYKN FNELNSDNPG
     ELNFDEFIEN SMVIKEEILY FDNDFKFDEK INMVYDHLHV LLLNSYTETI RVLSQDIDSN
     VLETRNVFEQ NSIKWHIYNS HQEKTINLHV FKKNNDNDEW NLICTRVEKF EIARPTLLKI
     KLFGDSYIIL ITRLGPLIYH FNESDRSISL IYFYYIYLSN KEIIPHYKKV YSKSTLPLPN
     YESFKYNDNW VLDAKHNKEI LLKYGVELLT FAIKEHKLEL IDEIYKECIN YFKQDLKNNR
     MFLSVITSTL PLLNEYYPEY ILRYSLDTTM IIDSPSFRIE YPNSNLHLFS FLYPQIINIT
     HSILWFKYNI LMRRIYNNHK ILFAIIIFIQ FLVILLTFPV YFAIFYLLSK YNYINDISES
     DMFSIYFIIP DIITSKFSKR LTTPTIIFMN PFINFVTYPK DYNWLSELIW PQSSPFVKTV
     NRDIYKTWSG ESLINFKWNN YGKHYYAIIW IGFMAFLGCF TAAATIPHID DNIRNKLLIS
     SIVLGVIHLS FEIRQMIYDF NKWIHDFWNL FDVIAYVLPI FTSIIWLQSS EINIISLLSF
     SCLFLDIKFL LFFRVFEYFG VYFAIIISVA KQIISFLVVL FIIIISFAHA FYILLIPRSQ
     FSFDQHTNND DPNNPWNLVT TYYQVFENGT VNPNPYIIQP PNGNTNMFVD FRTAIFAMYK
     FLTGDSSALS NWSYTDNPSL AIMIVLFSLL IVVYLMNLFI GLLNNAIEKD NDRVSYLVQK
     AEILAEIELF YLLPHQRRWY TWFPDVIYYY ANVDKSREKI KEMNDKGEWK TNEFPELRKN
     LMEKLNIQLI NETSLQNILA EIQEMKQKLQ
//