ID A0A2Z6SE61_9GLOM Unreviewed; 980 AA.
AC A0A2Z6SE61;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=RclHR1_07880006 {ECO:0000313|EMBL:GBC08032.1};
OS Rhizophagus clarus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Glomerales; Glomeraceae; Rhizophagus.
OX NCBI_TaxID=94130 {ECO:0000313|EMBL:GBC08032.1, ECO:0000313|Proteomes:UP000247702};
RN [1] {ECO:0000313|EMBL:GBC08032.1, ECO:0000313|Proteomes:UP000247702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HR1 {ECO:0000313|EMBL:GBC08032.1,
RC ECO:0000313|Proteomes:UP000247702};
RA Kobayashi Y.;
RT "The genome of Rhizophagus clarus HR1 reveals common genetic basis of
RT auxotrophy among arbuscular mycorrhizal fungi.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBC08032.1}.
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DR EMBL; BEXD01004190; GBC08032.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z6SE61; -.
DR STRING; 94130.A0A2Z6SE61; -.
DR Proteomes; UP000247702; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR025476; Helitron_helicase-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45786:SF82; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR45786; DNA BINDING PROTEIN-LIKE; 1.
DR Pfam; PF14214; Helitron_like_N; 1.
DR Pfam; PF05970; PIF1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000247702}.
FT DOMAIN 319..497
FT /note="Helitron helicase-like"
FT /evidence="ECO:0000259|Pfam:PF14214"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..30
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 980 AA; 113373 MW; ECF66284ACE03F1E CRC64;
MFESETSEQR KKRLYKENKS RYRKKQKTKH SDRQQYSNIM RHELGRMDQI CIHCNAKFWI
DERDQKSSQA SSSFAVCCAG GKVSLPPLLK PPSYILDLYT SSSSDAALFR KNIRGYNNIL
ACTSFGANID EKFQGQGVSN FRIHGQVYHR IGSLLPENEH FPAFAQLYIY DTEHENENRQ
NIMQDLNNDI LLNLQNMLDE CNPYIRSFRQ VRDIILSNAT SQISMVIHSD RTHNPHCYNA
PTSSDVAAII IGDGYDVNPT NRNICLRLHD GGLQIISETH PSYDPLYYVL LFPRGDDGWH
INIPLIGLSK RKRITPMQFY SYRLQIRDGD WLQYAGRLYQ QYIVDQYAKI EQERLNYLKL
NQTILRTEMY QGTVDAIDAG DISNNIGRRI ILPSSFTGGP RQMYQLYQDA MSIVSHFGKP
DLFITFTCNP KWPEITRELL PNQNAADRPD LTARVFHLKL QKLLKDLNIN HWFGKVIAYV
YVVEFQKRGL PHAHILLILA PEDKIYSIEK YDSIVSAEIP DPAIYPLAYE TVTTCMMHGP
CGILNPSAPC MKDATKYNAH INVEICNSIL AIKYLYKYVY KGHDRATITL SQTNNTQTSA
NIETIDEIKM YLDARYISSS ESIWRIFHYR LHNHIPSVQR LAVHLPNQQS ITFQDGDNLQ
HIVDYATTRM TTLTAWFQEN LENIAAHEYK YTDFPLYYTW NKSQCKWNPR KSATGAIGRL
YMVQPSEGER YYLRILLTHI KGATSFDNLK TVNGYTCRTF KEACIHLGLL QNDNEWDICL
YEASKINTGQ QLRHLFAMIL LYCQPAAPEK LWNKYKSALC EDILYQYHQT TIVNNIIECR
ALNQLNQYLL SNGKSLKDFP DMHLLLENMP DVDNDNNNLD QLIQEERLLY NIMHLESILH
NNIPLLNAEQ HAIYNAVIQA FEHNSSECFF VDGPGGTGKT FLYNTILAKV RLCGEIALPL
NQEKKRKEIK CKKKLVINHN
//
