ID A0A2Z6TAC9_9LACO Unreviewed; 780 AA.
AC A0A2Z6TAC9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Antimicrobial peptide ABC transporter ATP-binding and permease protein {ECO:0000313|EMBL:GBG04873.1};
GN ORFNames=LrDSM24759_07870 {ECO:0000313|EMBL:GBG04873.1};
OS Lactobacillus rodentium.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=947835 {ECO:0000313|EMBL:GBG04873.1, ECO:0000313|Proteomes:UP000257317};
RN [1] {ECO:0000313|Proteomes:UP000257317}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24759 {ECO:0000313|Proteomes:UP000257317};
RA Tanizawa Y., Tohno M., Endo A., Arita M.;
RT "New taxa in the Lactobacillus gasseri group.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Macrolide
CC exporter (TC 3.A.1.122) family. {ECO:0000256|ARBA:ARBA00038388}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBG04873.1}.
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DR EMBL; BFBY01000005; GBG04873.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2Z6TAC9; -.
DR OrthoDB; 2079174at2; -.
DR Proteomes; UP000257317; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR017911; MacB-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42798:SF6; ABC TRANSPORTER, ATP-BINDING PROTEIN; 1.
DR PANTHER; PTHR42798; LIPOPROTEIN-RELEASING SYSTEM ATP-BINDING PROTEIN LOLD; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF02687; FtsX; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:GBG04873.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000257317};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 263..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 743..763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..240
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 780 AA; 85748 MW; 9A2AD4B479FFD4C2 CRC64;
MLQLEHLMKT YKVGDTITHA LNDVTINFRN HEFVAILGPS GSGKTTLLNV IGGLDHYDSG
DIIINGKSTK NFTQTDWDAY RNNTVGFIFQ SYNLIPHLSI IENVELGMTL SGVDSKERHE
KAIAALKKVG LGEHIYKKPN QLSGGQMQRV AIARAIANDP DILLCDEPTG ALDTKTSKDI
MKIIKELSKD KLVIMVTHNP ELADEYASRI VHFQDGKILS DSDPYTPPKD VKDTFHLKKT
KMSYWNALKL SFTNIMTKKG QTFLTAFASS IGIIGIAIVL ALSHGFQKQI DETQTKTLAQ
FPISISQTAT DLSANSNREK SNNKNVKYRG YLTAAIPDNE KNTHQNHITQ AYLNYIKKIN
PAYANNISFI RGTQLNLLSN NDGKISKVEF SNTNNSQNSL ASAQLQSMNT MGINTNVFPT
TLDSKKNSFL KTNYQLLEGK WPKASTDVVL VLNNKDEANL NALTNLGLKV KDGQKIDLSK
LIGKKFKLVT NNDYYQKLST GTYVPKTPDQ AMYNSASTTI TLAGVIRSKN NSQMALLDNG
IAYSDNLTKK IINQNKNSEI VQAQKNSNLN VLTNQPLANS QKEQLLASLG GSSLPSSILI
YPTSFDSKDK ILSYLDKWNK GKKSSAKIIY TDMSGTVTQL TGGVLSGITT VLVAFAGISL
ITSMIMIGIL TYTSVLERTK EIGILKALGA RKRDITRVFD AETFILGAFS GVLGIFIAYL
LTFPISAIIY NMTDMPNVAQ LDWLQAIILV VIATILTMIG GHLPAKMAAK RDAAEALRSE
//
