ID A0A314KPA8_NICAT Unreviewed; 531 AA.
AC A0A314KPA8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 13-SEP-2023, entry version 13.
DE RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177};
DE EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};
GN Name=FMO1_2 {ECO:0000313|EMBL:OIT31186.1};
GN ORFNames=A4A49_33792 {ECO:0000313|EMBL:OIT31186.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT31186.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT31186.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT31186.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|RuleBase:RU361177};
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183,
CC ECO:0000256|RuleBase:RU361177}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT31186.1}.
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DR EMBL; MJEQ01001336; OIT31186.1; -; Genomic_DNA.
DR RefSeq; XP_019227744.1; XM_019372199.1.
DR AlphaFoldDB; A0A314KPA8; -.
DR STRING; 49451.A0A314KPA8; -.
DR EnsemblPlants; OIT31186; OIT31186; A4A49_33792.
DR GeneID; 109209035; -.
DR Gramene; OIT31186; OIT31186; A4A49_33792.
DR KEGG; nau:109209035; -.
DR OrthoDB; 5487623at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF217; FLAVIN-CONTAINING MONOOXYGENASE; 1.
DR Pfam; PF00743; FMO-like; 2.
DR PIRSF; PIRSF000332; FMO; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU361177};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU361177}; Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU361177};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU361177};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 287..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 531 AA; 60975 MW; 818EAB1102014C9B CRC64;
METHVNGEIN VEKNKKQIGI IGAGISGLVA CKHALEQGFN PIIFESSNCI GGVWSNTIES
TKLQTPKDLY QFSDFSWPTS VTETFPNHYQ VKDYIESYAL HFNILKHIQF NTKVVSIDYC
CEDDGEEMAA GCQNLWGGTG QAFSPKCKWV VTVMDLLRSL HPHKVYEVDF IILCIGKFSG
LPNIPHFPMN KGPEVFNGKV IHAMDYAEMG SVNATAMVKD KRVTVIGFQK SAIDLAAEVA
RLNGVKHPCT LLLRRVHWTV PEGFLKLSFR NLNRFSELMI HKPREGFFLW FLAILLSPLL
WIFSKFAESY LKWIYPLKKY NMIPDHGFLR QISSCMFTVL PADFYKRVEE GSLILKKSKS
YCFCKNGLII DEENLPLNTD LVIFATGYRS DDKLCNIFTS TYFQKCITGS STPFYRECIH
PRIPQLAILG YSESPAILYT TEMQSKWLAH FLAGKFKLPT IAEMEEDVLR WEKCMQRYAC
KYYKRACVSV LLQIYCNDLL CRDMNLNPRR KKKMLSELFA PYKPSDYQRS V
//
