ID A0A314KSG1_NICAT Unreviewed; 492 AA.
AC A0A314KSG1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 22-FEB-2023, entry version 12.
DE SubName: Full=2-oxoisovalerate dehydrogenase subunit alpha 1, mitochondrial {ECO:0000313|EMBL:OIT32262.1};
GN ORFNames=A4A49_25158 {ECO:0000313|EMBL:OIT32262.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT32262.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT32262.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT32262.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT32262.1}.
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DR EMBL; MJEQ01001092; OIT32262.1; -; Genomic_DNA.
DR RefSeq; XP_019226052.1; XM_019370507.1.
DR AlphaFoldDB; A0A314KSG1; -.
DR STRING; 49451.A0A314KSG1; -.
DR EnsemblPlants; OIT32262; OIT32262; A4A49_25158.
DR GeneID; 109207571; -.
DR Gramene; OIT32262; OIT32262; A4A49_25158.
DR KEGG; nau:109207571; -.
DR OrthoDB; 952at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR43380:SF5; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA 1, MITOCHONDRIAL-LIKE ISOFORM X1; 1.
DR PANTHER; PTHR43380; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609}.
FT DOMAIN 155..451
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 492 AA; 55339 MW; CE7EBA4FA4322727 CRC64;
MAILISRSRN FNHFLLSTRF HFLSLLNQTS SETFFRHAKT SPLTTAAGGG FTKPTAAFSG
ESAAIFRAER FQSNKGGEQL NTLYYEEDDH HQIIDENQVM DFPGGQLPIT PQMKFIAESS
EKRLPCYRVL DDDGYPIPGS IFEEVSKELA VKMYSSMVAL QVMDTIFYEA QRQGRLSFYL
TTAGEEGINI ASAAALTIDD FILPQYREVG VILWRGFSLK EIANQLFGNK FDYGKGRQMP
CHHGSNELNH LTISSPIATQ IPQAAGVAYS LKMDKKEACA VTYFGDGSTS EGDFHAALNF
AAVLDAPVVF ICRNNGWAIS TPVNEQFRSD GVASKGQAYG IRSIRVDGND VLATYSAIRA
AREMAIKEQK PILVEAMTYR VAHHSTSDDS TKYRPVEEIE HWKTEKSPIS RFRKWIQRNG
WWNDENESEL RGDVRKQVLQ AMQGAEKVEK PPLTDLFTDV YDKVPLNLQE QHKFIRDAVK
KSPKEYPSDV PI
//
