ID A0A314KWQ9_NICAT Unreviewed; 289 AA.
AC A0A314KWQ9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=cysteine dioxygenase {ECO:0000256|ARBA:ARBA00013133};
DE EC=1.13.11.20 {ECO:0000256|ARBA:ARBA00013133};
GN Name=PCO2_2 {ECO:0000313|EMBL:OIT33971.1};
GN ORFNames=A4A49_32412 {ECO:0000313|EMBL:OIT33971.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT33971.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT33971.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT33971.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-cysteine + O2 = 3-sulfino-L-alanine + H(+);
CC Xref=Rhea:RHEA:20441, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:35235, ChEBI:CHEBI:61085; EC=1.13.11.20;
CC Evidence={ECO:0000256|ARBA:ARBA00024284};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20442;
CC Evidence={ECO:0000256|ARBA:ARBA00024284};
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SIMILARITY: Belongs to the cysteine dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00006622}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT33971.1}.
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DR EMBL; MJEQ01000789; OIT33971.1; -; Genomic_DNA.
DR RefSeq; XP_019223563.1; XM_019368018.1.
DR AlphaFoldDB; A0A314KWQ9; -.
DR STRING; 49451.A0A314KWQ9; -.
DR EnsemblPlants; OIT33971; OIT33971; A4A49_32412.
DR GeneID; 109205311; -.
DR Gramene; OIT33971; OIT33971; A4A49_32412.
DR KEGG; nau:109205311; -.
DR OrthoDB; 764393at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0017172; F:cysteine dioxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070483; P:detection of hypoxia; IEA:UniProt.
DR CDD; cd20289; cupin_ADO; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR012864; PCO/ADO.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR PANTHER; PTHR22966:SF50; CYSTEINE DIOXYGENASE; 1.
DR PANTHER; PTHR22966; UNCHARACTERIZED; 1.
DR Pfam; PF07847; PCO_ADO; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609}.
SQ SEQUENCE 289 AA; 32674 MW; 86BF1358760C77CC CRC64;
MNIGRILLTK KSLLTGRTYS HLSKKKMKKK TKKESERRKL IRKRLSRKKN MVQKLYDTCK
EVFVNGKAGY VPPPSDIHRL KSVLDGLEPK DIKLTVPSLE FSSRSGTGDE APLVTYIKLH
ECNKFSIGIF CLPPCGVIPL HNHPGMTVFC KLLAGTMHAT SYDWVQNHQQ FNHCEQQSGI
RLAKVHFDAD ITAPCDASVL FPESGGNLHC FKALTHCILL DVLGPPYSES EGRHCTYYQD
FTYDCCSGMT EDVKKVKVEE DGTRYAWLEE RNEQFVVLGG TYDGPTIKI
//
