ID A0A314L5Y4_NICAT Unreviewed; 948 AA.
AC A0A314L5Y4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Coatomer subunit beta {ECO:0000256|PIRNR:PIRNR005727};
DE AltName: Full=Beta-coat protein {ECO:0000256|PIRNR:PIRNR005727};
GN ORFNames=A4A49_19463 {ECO:0000313|EMBL:OIT36988.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT36988.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT36988.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT36988.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBUNIT: Oligomeric complex that consists of at least the alpha, beta,
CC beta', gamma, delta, epsilon and zeta subunits.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005727}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|PIRNR:PIRNR005727};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR005727}. Cytoplasmic vesicle, COPI-coated
CC vesicle membrane {ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane
CC protein {ECO:0000256|PIRNR:PIRNR005727}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR005727}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT36988.1}.
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DR EMBL; MJEQ01000364; OIT36988.1; -; Genomic_DNA.
DR RefSeq; XP_019263645.1; XM_019408100.1.
DR RefSeq; XP_019263646.1; XM_019408101.1.
DR AlphaFoldDB; A0A314L5Y4; -.
DR STRING; 49451.A0A314L5Y4; -.
DR EnsemblPlants; OIT36988; OIT36988; A4A49_19463.
DR GeneID; 109241366; -.
DR Gramene; OIT36988; OIT36988; A4A49_19463.
DR KEGG; nau:109241366; -.
DR OrthoDB; 151169at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR011710; Coatomer_bsu_C.
DR InterPro; IPR016460; COPB1.
DR InterPro; IPR029446; COPB1_appendage_platform_dom.
DR PANTHER; PTHR10635; COATOMER SUBUNIT BETA; 1.
DR PANTHER; PTHR10635:SF4; COATOMER SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF07718; Coatamer_beta_C; 1.
DR Pfam; PF14806; Coatomer_b_Cpla; 1.
DR PIRSF; PIRSF005727; Coatomer_beta_subunit; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005727};
KW Cytoplasmic vesicle {ECO:0000256|PIRNR:PIRNR005727};
KW ER-Golgi transport {ECO:0000256|PIRNR:PIRNR005727};
KW Golgi apparatus {ECO:0000256|PIRNR:PIRNR005727};
KW Membrane {ECO:0000256|PIRNR:PIRNR005727};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005727}.
FT DOMAIN 21..466
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT DOMAIN 669..807
FT /note="Coatomer beta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07718"
FT DOMAIN 813..940
FT /note="Coatomer beta subunit appendage platform"
FT /evidence="ECO:0000259|Pfam:PF14806"
FT REGION 490..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 105725 MW; 1C149EBF6D6FEE67 CRC64;
MEKSCSLLIH FDKGTPALVN EIKEALEGND VPAKVDAMKK AVMLLLNGET LPQLFITIIR
YVLPSEDHTI QKLLLLYLET IEKTDSKGSM LPEMVLICQN LRNNLQHPNE YIRGVTLRFL
CRLHEVDIIE PLIPSIMSNL EHRHPYVRRN AILAVMAVYK LPQGEQLLAD APEKIENVLT
TEQDPSAKRN AFLMLFQCAQ EHAVNYLLTH VDRVSDWGEL LQMVVLDLVR KVCRTNKGEK
GKYIKIIISL LIVPSAAVVY ECAGTLVSLS SAPTAIRAAA NTYCQLLQSQ SDNNVKLIVL
DRLNELKSSH REIMVDMIMD VLRALSSPNL DIRRKTLDIV LELITPRNIN EVVLTLKKEV
MKTQSGELEK NGEYRQMLIQ AIHSCAVKFP EVASTVVHLL MDFLGDNNVA SAIDVVVFVR
EIIETNPKLR VSIVTRLLDT FYQIRAARVC SCALWIIGEY CLSLSEVESG IATIKQCLGD
LPFYSVSEKG EANDSSKKSQ QVNSTTVSSR RPAVLADGTY ATQSAASETV FSPATVVQGS
LTTGNLRSLL LTGDFFLGAV VACTLTKLIL RLEEVQPSKV EVNKATTNAL LIMVSMIQLG
QSSVLPHPID NDSYDRIILC IRLLCNTGNE VRKIWLNSCH ESFVTMLSDK QLRETEEIKA
KAQISHSQPD DLIDFYHLKS RRGMSQLELE DAVHDDLKRA TGEFVKDEND ANRLNRVLQL
TGFSDPVYAE AYVTVHHYDI VLDVTVINRT KETLQNLCLE LATMGDLKLV ERPQNYTLAP
ESSKQIKANI KVSSTETGVI FGNIVYESSN VLERTVVVLN DIHIDIMDYI SPAVCSDAAF
RTMWAEFEWE NKVAVNTVIQ EEKEFLDHII KSTNMKCLTA LSALEGQCGF LAANLYAKSV
FGEDALVNVS IEKQADGKLS GYIRIRSKTQ GIALSLGDKI TLKQKGGT
//
