ID A0A314L9Q3_NICAT Unreviewed; 340 AA.
AC A0A314L9Q3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Protein downy mildew resistance 6 {ECO:0000313|EMBL:OIT38312.1};
GN Name=DMR6_2 {ECO:0000313|EMBL:OIT38312.1};
GN ORFNames=A4A49_03164 {ECO:0000313|EMBL:OIT38312.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:OIT38312.1, ECO:0000313|Proteomes:UP000187609};
RN [1] {ECO:0000313|EMBL:OIT38312.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT38312.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056, ECO:0000256|RuleBase:RU003682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OIT38312.1}.
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DR EMBL; MJEQ01000217; OIT38312.1; -; Genomic_DNA.
DR RefSeq; XP_019261688.1; XM_019406143.1.
DR AlphaFoldDB; A0A314L9Q3; -.
DR EnsemblPlants; OIT38312; OIT38312; A4A49_03164.
DR GeneID; 109239565; -.
DR Gramene; OIT38312; OIT38312; A4A49_03164.
DR KEGG; nau:109239565; -.
DR OrthoDB; 1057251at2759; -.
DR Proteomes; UP000187609; Unassembled WGS sequence.
DR GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IEA:UniProt.
DR GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009805; P:coumarin biosynthetic process; IEA:UniProt.
DR GO; GO:0002238; P:response to molecule of fungal origin; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47991:SF172; HYOSCYAMINE 6-DIOXYGENASE-LIKE; 1.
DR PANTHER; PTHR47991; OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Vitamin C {ECO:0000256|ARBA:ARBA00022896}.
FT DOMAIN 192..290
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 340 AA; 38147 MW; 11B90E38A825D664 CRC64;
MADLISSWSK VETVPPSHCI PLHERPLDPV PIAKEIPVIN LEKAKGEERA VIVQQLRKAC
EEYGFFQIIS HGVPEDLMKE AMKVYREFFS LPVEEKANYA KEATNNTSRG AATLYSSNAK
HYDSEEHRYW RDVLEHSCNV DGEDKNTWPH NPPRYREVIG SYSAEVRKLS KIILGLVSEG
LGLEAGYFDK DLRQRMLVNH YPACPDPCLT LGVGGHCDPN LISIIQQDAY GLQILKDEKW
IGVEPIPNAF VVNSGLPLTV ISNGKLASVA HRVVTNTTQP RTSIGTFICP DDIVEPAKLL
IDSGNPPLFK SFKWGEEFLP HYLSKKSVYH AALEPFKIEV
//
