ID   A0A315V6Z0_GAMAF        Unreviewed;       740 AA.
AC   A0A315V6Z0;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   22-FEB-2023, entry version 17.
DE   RecName: Full=J domain-containing protein {ECO:0000259|PROSITE:PS50076};
GN   ORFNames=CCH79_00014360 {ECO:0000313|EMBL:PWA14703.1};
OS   Gambusia affinis (Western mosquitofish) (Heterandria affinis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Gambusia.
OX   NCBI_TaxID=33528 {ECO:0000313|EMBL:PWA14703.1, ECO:0000313|Proteomes:UP000250572};
RN   [1] {ECO:0000313|EMBL:PWA14703.1, ECO:0000313|Proteomes:UP000250572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NE01/NJP1002.9 {ECO:0000313|EMBL:PWA14703.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PWA14703.1};
RX   PubMed=29703783;
RA   Hoffberg S.L., Troendle N.J., Glenn T.C., Mahmud O., Louha S., Chalopin D.,
RA   Bennetzen J.L., Mauricio R.;
RT   "A High-Quality Reference Genome for the Invasive Mosquitofish Gambusia
RT   affinis Using a Chicago Library.";
RL   G3 (Bethesda) 8:1855-1861(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWA14703.1}.
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DR   EMBL; NHOQ01002778; PWA14703.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A315V6Z0; -.
DR   STRING; 33528.ENSGAFP00000009247; -.
DR   Proteomes; UP000250572; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030544; F:Hsp70 protein binding; IEA:InterPro.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0051083; P:'de novo' cotranslational protein folding; IEA:InterPro.
DR   GO; GO:0006450; P:regulation of translational fidelity; IEA:InterPro.
DR   CDD; cd06257; DnaJ; 1.
DR   CDD; cd00167; SANT; 1.
DR   Gene3D; 1.10.287.110; DnaJ domain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.8.840; Ribosome-associated complex head domain; 1.
DR   InterPro; IPR001623; DnaJ_domain.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR032003; RAC_head.
DR   InterPro; IPR042569; RAC_head_sf.
DR   InterPro; IPR001005; SANT/Myb.
DR   InterPro; IPR044634; Zuotin/DnaJC2.
DR   PANTHER; PTHR43999; DNAJ HOMOLOG SUBFAMILY C MEMBER 2; 1.
DR   PANTHER; PTHR43999:SF1; DNAJ HOMOLOG SUBFAMILY C MEMBER 2; 1.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF16717; RAC_head; 1.
DR   SMART; SM00271; DnaJ; 1.
DR   SMART; SM00717; SANT; 1.
DR   SUPFAM; SSF46565; Chaperone J-domain; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   4: Predicted;
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000250572}.
FT   DOMAIN          85..158
FT                   /note="J"
FT                   /evidence="ECO:0000259|PROSITE:PS50076"
FT   REGION          47..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          291..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          427..446
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..66
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   740 AA;  84461 MW;  DECE0E6E32D56583 CRC64;
     MLLEARDNEE TTVFKAAAAS VQVLVEPVGR WFEAYIRRRS RNVSASFQEL EEEEESSEES
     EDEELQLEEH PMLRTLDPKD WKNQDHYAVL GLPHLRYKAT QKQIKAAHKS IVLKHHPDKR
     KAAGEQIVEG DNDYFTCITK AIEILSDPVK RRAFDSVDPT FDNSVPSKSE GKENFFEVFA
     PVFTRNARWS SKKHGPSLGT MDSSFEEVDN FYSFWYNFDS WREFSYLDEE EKEKAECRDE
     RRWIEKQNRA SRAQRKKEEM NRIRTLVDTA YSCDPRIKKF KEEEKARKEA EKKAKAEAKK
     KEQEEKERVR QAEREAARLA KEKEEEEARQ AALQAKKEKE IQKKAIKKER QKLRTTCKNW
     NYFADSEADS VKMMEEVEKL CDRLELTSLQ SLNEILASAS KEDSKAAVEK QVEEVNAQLQ
     KEKDAEVQAR QAARSAEQAS GGAGGGKGWY EDDLQLLIKA VNLFPAGTNA RWEVIANYMN
     LHSTSGMRRT AKDVINKAKN LQKLDPVQKD EINKKAYEKF KKEHTSVPPS IDNALPSERF
     DEHLKPSLIL TTPPPNERSQ FPIRVLATMR GMVSGGTEEE LGLRLDPGWE VFQSGTWPNC
     GVPGGKHLIR RKGRNLGQKS LGKEPANMFT FWKLFLCHHI GAQDGPAQCR GLVRCGVQVV
     KNHFLQVGLH FLHLPQDHAS LPLDLRLAQR AVLDDVGQDL DSWGKKKTDA GSRTVGLANL
     SIGWLSCPAP RGRSLEKALA
//