ID A0A315VVA1_GAMAF Unreviewed; 1671 AA.
AC A0A315VVA1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=LIM zinc-binding domain-containing protein {ECO:0000259|PROSITE:PS50023};
DE Flags: Fragment;
GN ORFNames=CCH79_00013896 {ECO:0000313|EMBL:PWA27213.1};
OS Gambusia affinis (Western mosquitofish) (Heterandria affinis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Gambusia.
OX NCBI_TaxID=33528 {ECO:0000313|EMBL:PWA27213.1, ECO:0000313|Proteomes:UP000250572};
RN [1] {ECO:0000313|EMBL:PWA27213.1, ECO:0000313|Proteomes:UP000250572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NE01/NJP1002.9 {ECO:0000313|EMBL:PWA27213.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PWA27213.1};
RX PubMed=29703783;
RA Hoffberg S.L., Troendle N.J., Glenn T.C., Mahmud O., Louha S., Chalopin D.,
RA Bennetzen J.L., Mauricio R.;
RT "A High-Quality Reference Genome for the Invasive Mosquitofish Gambusia
RT affinis Using a Chicago Library.";
RL G3 (Bethesda) 8:1855-1861(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA27213.1}.
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DR EMBL; NHOQ01001073; PWA27213.1; -; Genomic_DNA.
DR Proteomes; UP000250572; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08368; LIM; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15551:SF3; LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15551; LIM DOMAIN ONLY 7; 1.
DR Pfam; PF15949; DUF4757; 2.
DR Pfam; PF00412; LIM; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000250572};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 1607..1671
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 150..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 902..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1097..1327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1352..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1555..1601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1001..1035
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1429..1482
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 153..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..773
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..949
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1098..1122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1188..1209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1352..1372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1375..1397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1555..1599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PWA27213.1"
FT NON_TER 1671
FT /evidence="ECO:0000313|EMBL:PWA27213.1"
SQ SEQUENCE 1671 AA; 185831 MW; C8FE07ECF78F19F1 CRC64;
AVTGKSFGDK DFRSALENGI LLCDNNSHGL RLSKSLLLPL LHRLLSAIKP GLVKKINRLP
TPIAGLDNLS VFLRGCEELG LKGSQLFDPG DLQDTSIRAN LKDSDCSRKL KNVLNTVFWL
GKAASGCPFY SGPNLNLKEF EGLLAQMKLE SDDGGDSSQK RSIRDSGYDC WDSERSESLS
PPQHTRDNSL DSLDSFGSRS QHSPSPDVVN RGNSDGRGSD SDADAPSRKP DVRKDDMLAR
RTASSDSRCP VPFNQFLPNR ANASCYIPTP RRKQHPEEGE QRSHLQTIPE QTKRTGFQQK
PPKTVTWAPE SQAEKLKQGE DLEVLEQRRL EKLKKAGIKV LPAAVRYNST VITEEKEARS
PSPNIILRSE NEFLSSHSPA CDSSSDGEQD VETRRVPDVH RDDLASRRVH RSAGNSRVHQ
FVPPPACTTK DRERWEGIRR ASQQTLQQTE ISEKKAVCDI ITRKDNPSLK EEDDEGEDEK
DKTMPNKQRD DLARRRGQSR PLPQRDGPMS FVSSFMSPAD VQKWERLRMT EPSEDRPVPV
CQACLQRTYG ISGSAKAGRG HGRVVTFGGL TEIEQPTEAL KSGGEEPESL RRLQSKATVA
MTTVDLGFQL SEGDRSVVMD GCAASPPPAE HRPWTAEPTP TAAEIDARFA LYEQRAQAED
EEEEEERIPD LQKDDMMARR TGAFLNQTAG SADFRRFLPP PGSGWSSRGE VAADAAPPSN
KEVLIGTRAA SQQPRIPEET PHRSLKPAVI RATTQTEGEP DESDRDKSIP DLDRDDMVAR
RSGTFQKAAV FRGNQGFKQF LPVPGSVRCN ISSETAGKQS GNRSKLRADM DGGRYFLRWN
EDTAVSMRFL LILALSLDRC FNSCVAMVAE LEAPPFKAPS SPTFPGLAGR QVPDAAVIDA
IGPSSSSSSS LTRLPNPPCP PSPHTWRVEE QVEVGREEEK SEDGKMRREK KPCWLEDELP
PIMSVSMGDM ANEDEAGHFP SLSPSRYERM HQQCNAFVEE EDQWQDDLAR WKNRRRSASQ
ELIKKEEERK RMEKRMKGNG VDCNKRKSIK TYKEIVEEKE RREAELCEAY RQAATPEEAA
LVLQRYALRF TISDATLDSL KLPRSTNKPN QFLNQTEQEH SQTSGADESE RLEHPNQQDT
DSLTEQERCG QTEDCHEKHQ SGVNLSSSSA PDALQLQDTN SHSEKLQSEQ LPEPRSHLTD
PHDEHKNQQD PGAPQSPTEP AAEPQLKHKL PSLPSAPSRP LPLLAAKPYC PPSCSPPEHK
HVEVQQLDGS VRLNGETAED FASLPDPLQE NPAVSSQHAQ EPDPPEDSAE QPEPPLTERP
APTSGSAISS LIAGRNCIIT TTIVTELTKT HVEPLHPDVQ DDAQDGATEM PTEKGDHQPV
QSPSSLPEYS PSVSEGLEES SVTIETPMLN LAKRVNHWVW DPNEERKRLE SWQQEQERLL
QEQYQKEQEK LKKEWEKAQL EVEEEERKHN EEERRILEET VAPLSPSASA QRQLERMVTA
PFSVAEENNN AAVRGNVSLH QNGQKIHTGS EDQHASKLHF FQDSGCDEQL PQKQEMWKTS
SLDRSPQTNQ TQNVKRSGSH DAVAGNQDVS PSAPQPPSAS RCVSGKRLCS GCSKPLGRGA
AMIIDTLGLF FHMQCFKCGV CKGQLGDATA GTDVRIRNGL LSCYECYIAS R
//
