ID A0A315WBT6_GAMAF Unreviewed; 516 AA.
AC A0A315WBT6;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Ephrin type-B receptor 2 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=CCH79_00020793 {ECO:0000313|EMBL:PWA33311.1};
OS Gambusia affinis (Western mosquitofish) (Heterandria affinis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Gambusia.
OX NCBI_TaxID=33528 {ECO:0000313|EMBL:PWA33311.1, ECO:0000313|Proteomes:UP000250572};
RN [1] {ECO:0000313|EMBL:PWA33311.1, ECO:0000313|Proteomes:UP000250572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NE01/NJP1002.9 {ECO:0000313|EMBL:PWA33311.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PWA33311.1};
RX PubMed=29703783;
RA Hoffberg S.L., Troendle N.J., Glenn T.C., Mahmud O., Louha S., Chalopin D.,
RA Bennetzen J.L., Mauricio R.;
RT "A High-Quality Reference Genome for the Invasive Mosquitofish Gambusia
RT affinis Using a Chicago Library.";
RL G3 (Bethesda) 8:1855-1861(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA33311.1}.
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DR EMBL; NHOQ01000073; PWA33311.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A315WBT6; -.
DR STRING; 33528.ENSGAFP00000022847; -.
DR Proteomes; UP000250572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0005003; F:ephrin receptor activity; IEA:InterPro.
DR CDD; cd10472; EphR_LBD_B; 1.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.60.40.1770; ephrin a2 ectodomain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR001090; Ephrin_rcpt_lig-bd_dom.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR InterPro; IPR001426; Tyr_kinase_rcpt_V_CS.
DR PANTHER; PTHR46877; EPH RECEPTOR A5; 1.
DR PANTHER; PTHR46877:SF11; EPHRIN TYPE-B RECEPTOR 2; 1.
DR Pfam; PF01404; Ephrin_lbd; 1.
DR Pfam; PF07699; Ephrin_rec_like; 1.
DR Pfam; PF00041; fn3; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00615; EPH_lbd; 1.
DR SMART; SM01411; Ephrin_rec_like; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS51550; EPH_LBD; 1.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS00790; RECEPTOR_TYR_KIN_V_1; 1.
DR PROSITE; PS00791; RECEPTOR_TYR_KIN_V_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000250572}.
FT DOMAIN 1..179
FT /note="Eph LBD"
FT /evidence="ECO:0000259|PROSITE:PS51550"
FT DOMAIN 301..411
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 412..509
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 516
FT /evidence="ECO:0000313|EMBL:PWA33311.1"
SQ SEQUENCE 516 AA; 57003 MW; 989C6A24EE303B77 CRC64;
MDSTTATAEL GWTINPSQGW EEVSGYDEHM NTIRTYQVCN VFDNSQNNWI RTRFIQRRGA
QRIHVQMKFS VRDCSSIPNV PGSCKETFNL YYYESDSDVA SKAFPPWMEN PWVKVDTIAA
DESFSQVELG GRIMKINSEV RSFGPVSRKG FYLAFQDYGA CMSIIAVKVY YRKCPRVIQN
GAVFPETLSG AESTSLVAAR GVCVPNGEEV DVPIKLYCNG DGEWMVPIGR CMCKAGHEAL
ENGTLCQACV SGFFKAAQGD EKCLQCPINS RTISDGATNC ICRNGYYRAD ADPPRMPCTT
VPSAPQRVIS MVNETSVRLE WSPPLESGGR EDVVYNIICK SCDSRRGSCT RCGDNVQFVP
RQLGLTDTGV SISDLLAHTQ YTFEIQAVNG VSDQSPYSPQ YTSANITTNQ AAPSAVSIIH
QVSRTPNSIT LSWSQPDQPN GVILDYELQY YEKNLAEGNS SLIRSQTNTA VIRALKPGTI
YVFQVRARTV AGFGSFSGKM YFQTITMGKT SCICLK
//
