ID   A0A315ZX67_9ACTN        Unreviewed;       660 AA.
AC   A0A315ZX67;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Histidine kinase/DNA gyrase B/HSP90-like ATPase {ECO:0000313|EMBL:PWJ49873.1};
GN   ORFNames=BXY45_12439 {ECO:0000313|EMBL:PWJ49873.1};
OS   Quadrisphaera granulorum.
OC   Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC   Quadrisphaera.
OX   NCBI_TaxID=317664 {ECO:0000313|EMBL:PWJ49873.1, ECO:0000313|Proteomes:UP000245469};
RN   [1] {ECO:0000313|EMBL:PWJ49873.1, ECO:0000313|Proteomes:UP000245469}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44889 {ECO:0000313|EMBL:PWJ49873.1,
RC   ECO:0000313|Proteomes:UP000245469};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWJ49873.1}.
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DR   EMBL; QGDQ01000024; PWJ49873.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A315ZX67; -.
DR   OrthoDB; 227596at2; -.
DR   Proteomes; UP000245469; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PWJ49873.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245469};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        43..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        135..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        264..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          560..657
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00387"
SQ   SEQUENCE   660 AA;  69718 MW;  500DABC99362890B CRC64;
     MLAGVVAIRA RVLSGALALL ALVCAGAVVV SGVRTPPTRA LDTVLLAFDL LPLTAALLTG
     WLLLRAPRHP GFTAYLAFAL VLFVLGTTHL AERAVTALSG PPRLLDAFTV LSCFGFLVVA
     YLFPDGRFVP GWSRWLIAGW GAAAALALAF PWDTFPPAAQ VLLGVLTTPL LLTLVGTQVH
     RYRAVSTPLE RQQTTWFLLA LTLQVTWYLA VVALPVHTIE ALPAAGRTAV AACGALVTTS
     LCVAIGGAVL RHRLFDVDLV VGRALVYGAL TAFTALSCAV VIGAAGLVQP ADTPAALVVA
     ATAVTALGMG PLRRAVQRRV NRWLYGLRDE PAAALGRLGE ELSATSDLDG AMSRIASTVR
     SALRSPRVRV QVFPEGAPPR EATAGAPATA LDQAATVDIR SDGALLGRID VAPRPWDRVS
     PRDLALVQRL ARHAAVAIRA GIVTEELQRS RAELILTREE ERHRLHRDLH DGLGPTLASL
     SQRIDLALRS LASDPARTRH LLDGAREGID EALAELHVVV ESLRPAALDR LGLVGAIAAA
     WSCDERVRVD GFTLPPLDPQ VEQAAYRIAM EAVSNAVRHA DATRCDVTVS LDHEDDGDGD
     GVLVLEIVDD GHGMPACPVP GAGLRTMRER TAELGGKLTT DSDRTGVRIV ARLPVTGGAA
//