ID   A0A316A7Q0_9ACTN        Unreviewed;       875 AA.
AC   A0A316A7Q0;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II {ECO:0000313|EMBL:PWJ53956.1};
GN   ORFNames=BXY45_10937 {ECO:0000313|EMBL:PWJ53956.1};
OS   Quadrisphaera granulorum.
OC   Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC   Quadrisphaera.
OX   NCBI_TaxID=317664 {ECO:0000313|EMBL:PWJ53956.1, ECO:0000313|Proteomes:UP000245469};
RN   [1] {ECO:0000313|EMBL:PWJ53956.1, ECO:0000313|Proteomes:UP000245469}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44889 {ECO:0000313|EMBL:PWJ53956.1,
RC   ECO:0000313|Proteomes:UP000245469};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWJ53956.1}.
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DR   EMBL; QGDQ01000009; PWJ53956.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A316A7Q0; -.
DR   OrthoDB; 2472181at2; -.
DR   Proteomes; UP000245469; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR020802; PKS_thioesterase.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR001031; Thioesterase.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF10; SURFACTIN SYNTHASE SUBUNIT 1; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SMART; SM00824; PKS_TE; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:PWJ53956.1};
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245469}.
FT   DOMAIN          544..622
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   875 AA;  91529 MW;  B2A7CC95921BD297 CRC64;
     MGWSGDREQG RGAFVALTAH EVHQHVVTRV RAVAAAQPGA LAVDDGSLRL DYAELERRAA
     ALSARIAAVA PAGEPVAVLL GQGATVAVAV LAVIGTGAPV VVLDSTTPVA RLRHYVELAG
     ATTVVTDAVR AADGAELCAR VVRADRSLVA LGEDGDPTAS ALAWPCSEEQ LDSRAPVVIV
     FTSGSTGRPK GVSAHSESVL HDATTNGRGC YGPGAVIANL LPMAFSAGIG LLLAGLATGS
     GQVLFDPRTR PVSELPGWLL QTGATVLAAS PAILRGAVAA LAPGEQLGHL KAVTTAGETI
     HAAEMQRLRA ALGPGCAVHN RYGSTETWLI AEHVIAPADS GPAGAVPVGR PVDGVSLHVV
     DEHGTRHDSG TGRLEVTSRW LSDGYWNAPE ATAAVFTDHA DGSRSYLTSD TATIDDDGVV
     RLLGRVDHSV KIRGHLVEPG EVDAVLHALP EVREAVVVGV VPSVDEGDDG DSAGTGRARL
     VAYVVPESAA LQIPELRRSV RAVLPSFMVP EQVVLLDALP RTERGKLDRS ALPPPPAVQV
     GAAPPRTDWE RVVASFVARA LDLDGVGAHD DFFELGGDSL AAEALMAAMA ASLDVPSGVL
     TTRLIAENPT VAELAEALRR RRRPGRDAAV VTFNATGTHR PLFVVAGAGG VALAFRRLAE
     RLGCDQPVIA LQARGLEGGG RPEWSVRSRA RHHLEQLRRA QPEGPYRLAG HSLGALVALD
     MAQQLREAGE EVESLMIIDS FPPDPDVAPP ALEGPLPQRA KILASILLTG VVQSRGLGHY
     DRFHLQGKLL QRRYRSQPWA GRALVLVAAD DPDADARSRW AQHLTGTWSL HRTGGDHTGV
     LQEPHVGPLA RLVRAELDAL DRLGADAVQR PAGAA
//