ID A0A316ABN6_9ACTN Unreviewed; 423 AA.
AC A0A316ABN6;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Threonine dehydrogenase-like Zn-dependent dehydrogenase {ECO:0000313|EMBL:PWJ54668.1};
GN ORFNames=BXY45_106111 {ECO:0000313|EMBL:PWJ54668.1};
OS Quadrisphaera granulorum.
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Quadrisphaera.
OX NCBI_TaxID=317664 {ECO:0000313|EMBL:PWJ54668.1, ECO:0000313|Proteomes:UP000245469};
RN [1] {ECO:0000313|EMBL:PWJ54668.1, ECO:0000313|Proteomes:UP000245469}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44889 {ECO:0000313|EMBL:PWJ54668.1,
RC ECO:0000313|Proteomes:UP000245469};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWJ54668.1}.
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DR EMBL; QGDQ01000006; PWJ54668.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316ABN6; -.
DR OrthoDB; 241504at2; -.
DR Proteomes; UP000245469; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000245469};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 26..142
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 217..290
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
FT REGION 178..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 44871 MW; 536D93DF513BE111 CRC64;
MRALTWQGKR KVSVETVPDP KIEEPTDAVV RITASGLCGS DLHLYEVMGP FLDPGDVLGH
EPMGVVEEVG PDVTHLRPGD RVVVPFNISC GRCPMCRSGL QSQCETTQNR DTGFGASLFG
YTKLYGQVPG GQAEYLRVPQ AHYGPIKVPD DVPDERYLYL SDVLPTAWQA VRYAGVTGGP
SASSTGTTGT TGTTTGSAAA SSWTPVVDSL VVLGLGPIGD MCTRIARHLG VSTVIGIDPV
PERRARAQAR GTTVIDPTSL DDSSDLVGAV RDLTAGRGAD AVIDAVGMEA HGSAAKAAHT
FVGFLPDAVA EKMMRTMGVD RLTALHSAVD LVRRGGTISL SGVYGGAADP MPMLYMFDRQ
LQLRMGQANV HRWVPEILPL LGDDDPLGVE GFATHHVPLD DAPAAYETFQ KKQDGAVKIV
FHS
//
