ID A0A316AY48_9MICO Unreviewed; 863 AA.
AC A0A316AY48;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:PWJ63288.1};
GN ORFNames=B0H03_10892 {ECO:0000313|EMBL:PWJ63288.1};
OS Rathayibacter iranicus NCPPB 2253 = VKM Ac-1602.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Rathayibacter.
OX NCBI_TaxID=1328868 {ECO:0000313|EMBL:PWJ63288.1, ECO:0000313|Proteomes:UP000245674};
RN [1] {ECO:0000313|EMBL:PWJ63288.1, ECO:0000313|Proteomes:UP000245674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-1602 {ECO:0000313|EMBL:PWJ63288.1,
RC ECO:0000313|Proteomes:UP000245674};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWJ63288.1}.
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DR EMBL; QGDV01000008; PWJ63288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316AY48; -.
DR OrthoDB; 7177610at2; -.
DR Proteomes; UP000245674; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 535..701
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT REGION 773..863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 786..809
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..834
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 863 AA; 86807 MW; 808751866F109D14 CRC64;
MSAVRAADVR LLPVAVASWA GAWSAGLLPV SAVLEWGAAA CATAWLVILL GAGLLVQARR
RRGRAALGGV LVAAAGAALA VTSVVVSAPG DHPEALRGAA ERRAITSVAV CVDSGPRPLA
TGGVWFEATA LRVGDVPVSA PVRVMLADPG GDIAVASELR LAARVGPGES AVGEMPLLNA
SAVLDHRAPE GAAGVAAMLR AHFLARTALI GGDAAGLLPG LATGDTSALD AGLEEDMRTA
SLTHLTAVSG ANCALVVVAG WAVAALLGAG RRLRTAAALA TLAAFVLLVT PEPSVVRAAV
MATVVLLARL GRRSGAAVPA LLASVVVLVV ADPAIAGRLG FVLSVLATAG LLLLAEPIAA
TLGRLLPRSL ALVLAVPTAA QLACQPVLVL VDPSVPVYGV LANLLAEPAA PAVTGLGLIG
CLLAPWWPGG ADVAIRLAAV PAWWIAAIAR AVASWPSPRL AWWSGLGGAV ALSALTLLAL
VLVSRSARLA RLRRIAAVSL ACALAATGGT AVATPLLRAA SVPDDWRVAL CDVGQGDAIL
LRGDEGVLLV DTGPDPAPLD ACLRLLGVER VALLVLTHYD LDHVGGLDAT LGRTDSALVG
PAAGRDDDRD RAALAGSGTV VREAVRGDAG TLGSLRWRVE WPEGGSALRG NEASVALRVD
IGPDGRGAPL SVALLGDLGA EEQGRVARLP VGRVDVVKVA HHGSADQASA LYDALGASIG
LISVGAGNDY GHPNPSLLAL LAERGVETLR SDVEGTVVLA SRTDGVVVWA SGSGASAAAS
EPRAQTVKWR RSDGRGTEGR RHGRQSPVAR EGGAREGGDP AARLEPDAAR PDRPDHGSGG
VPGRPCAAVS SRVSARRGSE PRG
//
