ID A0A316C6S3_PSESE Unreviewed; 1012 AA.
AC A0A316C6S3;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Pyruvate carboxylase {ECO:0000313|EMBL:PWJ84973.1};
GN ORFNames=C7441_104241 {ECO:0000313|EMBL:PWJ84973.1};
OS Pseudaminobacter salicylatoxidans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Pseudaminobacter.
OX NCBI_TaxID=93369 {ECO:0000313|EMBL:PWJ84973.1, ECO:0000313|Proteomes:UP000245396};
RN [1] {ECO:0000313|EMBL:PWJ84973.1, ECO:0000313|Proteomes:UP000245396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6986 {ECO:0000313|EMBL:PWJ84973.1,
RC ECO:0000313|Proteomes:UP000245396};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWJ84973.1}.
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DR EMBL; QGGG01000004; PWJ84973.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316C6S3; -.
DR STRING; 1192868.GCA_000304395_02815; -.
DR Proteomes; UP000245396; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004736; F:pyruvate carboxylase activity; IEA:InterPro.
DR GO; GO:0006094; P:gluconeogenesis; IEA:InterPro.
DR GO; GO:0006090; P:pyruvate metabolic process; IEA:InterPro.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.10.600.10; pyruvate carboxylase f1077a mutant domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR005930; Pyruv_COase.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR NCBIfam; TIGR01235; pyruv_carbox; 1.
DR PANTHER; PTHR43778; PYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR43778:SF2; PYRUVATE CARBOXYLASE, MITOCHONDRIAL; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00866; CPSASE_1; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Pyruvate {ECO:0000313|EMBL:PWJ84973.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245396}.
FT DOMAIN 2..462
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 128..326
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 539..807
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 1012 AA; 111290 MW; C462C9A5A3DFEC41 CRC64;
MPISKILVAN RSEIAIRVFR AANELGLKTV AIWAEEDKYS LHRFKADESY QVGRGPHLTR
DLGPIESYLS IEEVLRVAKL SGADAIHPGY GLLAESPEFA EACAEAGITF IGPRPDTMRR
LGNKVAARNL AVEVGVPVIP ATDPLPDDVE AVKKLAADVG YPLMLKASWG GGGRGMRVIR
SEADLAREVM EGKREAKAAF GKDEVYLEKL IERARHVEVQ VLGDTHGNAV HLFERDCSIQ
RRNQKVVERA PAPYLDAVQR GELCDHALKI ARATDYVGAG TVEFLMDADS GKFYFIEVNP
RIQVEHTVTE EVTGIDIVKA QIHILNGLAI GKPETGVPNQ SEIRLNGHAL QCRITTEDPE
HNFIPDYGRI TAYRGATGFG IRLDGGTAYS GAVITRYYDP LLEKVTAWAP TPSEAIARMH
RALREFRIRG VSTNLTFLEA IITHPSFQSN SYTTKFIDST PELFAQVKRQ DRATKLLNYL
ADVTVNGHPE TRGRALPDPE AAAPVIPWFT GSIPDGTKQR FDALGPQKFA AWMREQKQVL
FTDTTMRDAH QSLLATRVRT YDIARIAGTY ARALPQLLSL ECWGGATFDV AMRFLTEDPW
ERLSKVREAA PNILLQMLLR GANGVGYTNY PDNVVQHFVK QAAAGGIDLF RVFDCLNWVE
SMRVAMDAVL AEGKLCEAAI CYTGDMLDPN RSKYDLKYYV GLTRELEAAG AHIISLKDMG
GLLKPAAARV LFKALREATD LPIHFHTHDT SGLGAATVLA AAEAGVDAVD AAMDAFSGNT
SQPCLGSIVQ ALRGDPRDPG LDPEWIRRIS FYWEAVRNQY AAFESDLKGP ASEVYLHEMP
GGQFTNLKEQ ARSLGLETRW HEVAQAYHDV NLMFGDIVKV TPSSKVVGDM ALMMVSQDLT
VTDVENPDKD IAFPESVVAM LRGDLGQAPG GWPAALQKKA LKGEKPITVR PGSLLKPADL
AASRKGLEEK LGRKVSEFEF ASWLMYPKVF SDFAATQETY GPVSVLPTPV YF
//
