ID A0A316EM30_9BURK Unreviewed; 415 AA.
AC A0A316EM30;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Membrane fusion protein (Multidrug efflux system) {ECO:0000313|EMBL:PWK32343.1};
GN ORFNames=C7419_107134 {ECO:0000313|EMBL:PWK32343.1};
OS Cupriavidus plantarum.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=942865 {ECO:0000313|EMBL:PWK32343.1, ECO:0000313|Proteomes:UP000245754};
RN [1] {ECO:0000313|EMBL:PWK32343.1, ECO:0000313|Proteomes:UP000245754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLV-132 {ECO:0000313|EMBL:PWK32343.1,
RC ECO:0000313|Proteomes:UP000245754};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-V): Genome sequencing
RT to study the core and pangenomes of soil and plant-associated
RT prokaryotes.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWK32343.1}.
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DR EMBL; QGGT01000007; PWK32343.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316EM30; -.
DR Proteomes; UP000245754; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000245754};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 74..307
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 308..374
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
SQ SEQUENCE 415 AA; 44067 MW; 0A4DC608C4C3C668 CRC64;
MMGQVRAVGA TMAAATAKHA DLRWWLCAMG GAALMLTACG RQEPPPAAAQ AVPVQVFQTR
AHDLPVTFEF VGQTQSDQAV DVRARVSGFL VKRNYVEGAM VRENQVLFEI DHKPFQTQLD
AAQAQLSQQK ARLDVARANL ARVKPLAAQN ALSQKDLDDA TGQFHSAVAG VEQATAEVET
QKLNLSYTYV RAPVDGVSSF GVLPVGAYVS TTNSLLTTVS TLSPMRINFS ISEPQTLEFR
AQQQNRQLVV PPDRHYSVSI VLADGSEYPH KGRITFADAT YSPQTGTFLV RAEMPNPNNE
LQPGQFVRVL VGGATRPNAI VVPQRAVMHG PKGDLVFIVD KEGKAQPRPV TVGELSGPMW
RIAQGLEAGE TVVVDGAGKL TAGAPVQVTG EAPLAAVGAG SASAPAKSAT PSATR
//
