ID A0A316FQ60_9GAMM Unreviewed; 727 AA.
AC A0A316FQ60;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=C8D97_106111 {ECO:0000313|EMBL:PWK50824.1};
OS Pleionea mediterranea.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Pleioneaceae; Pleionea.
OX NCBI_TaxID=523701 {ECO:0000313|EMBL:PWK50824.1, ECO:0000313|Proteomes:UP000245790};
RN [1] {ECO:0000313|EMBL:PWK50824.1, ECO:0000313|Proteomes:UP000245790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25350 {ECO:0000313|EMBL:PWK50824.1,
RC ECO:0000313|Proteomes:UP000245790};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWK50824.1}.
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DR EMBL; QGGU01000006; PWK50824.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316FQ60; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000245790; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR029491; Helicase_HTH.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF14493; HTH_40; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:PWK50824.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245790}.
FT DOMAIN 50..218
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 240..388
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 550..630
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 81337 MW; 43007771765BFDAC CRC64;
MSSLIKSSSQ NKSSSQINPT PQSSSSLSPL TILQTQFGYS AFRDPQQAII ESVIEGRDTT
VIMPTGGGKS LCYQIPAIAL EGTGIVVSPL IALMDDQVTA LKQNGVRAAY LNSTMNMAQV
QEVEQMLLQQ QLDLLYVAPE RLMMDRFINL LSRTRIALFA IDEAHCVSQW GHDFRPEYIQ
LSALAELFPN VPRIALTATA DDTTRKEIID KLSLDHSNAF ICGFDRPNIQ YRVQQGSKNA
KQALLDFIQQ EHPDDAGIVY CLSRKKVEQT ADWLTSKGLT ALPYHAGLSS DMRRQHQQRF
LQQEGVIIVA TIAFGMGIDK PDVRFVAHLN LPKSIEAYYQ ETGRAGRDGL PATAWMSYGL
NDVITLRQML ETSDAPEQHK RVERHKLDAV LGFAEITDCR RQSLLGYFGE ALAQPCGNCD
TCLTPVETWN ATEVAQKALS TVYRTGQRFG VNHLIDVLLG KENVKVKNFK HDELSVYGIG
QELDVSQWRS VFRQLISRNL LKVDLEGYGG VQLTEACRPV LKGESELYLR KDVTAVTQKK
KARGRPEQIK QSDFNLWEAL REARMTVAKD NKLAPYMVFN DATLMAMVES KPTSLSQMAM
ISGVGERKLE LYGELFLQVI ADNAESTRPT AEESLKLFQQ DKTVAEIAHQ RGLAESTVFS
HLATAIQQGQ LLIDDILDIN DLDLNLVHQL FLEQEGEKVR MKPVFEALDG KFSYGELQCI
KAHFLLE
//
