ID A0A316G9R8_9RHOB Unreviewed; 357 AA.
AC A0A316G9R8;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Sensory histidine kinase/phosphatase NtrB {ECO:0000256|ARBA:ARBA00039567};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
DE AltName: Full=Nitrogen regulation protein NR(II) {ECO:0000256|ARBA:ARBA00042313};
DE AltName: Full=Nitrogen regulator II {ECO:0000256|ARBA:ARBA00043094};
GN ORFNames=C8D95_102290 {ECO:0000313|EMBL:PWK57644.1};
OS Silicimonas algicola.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=1826607 {ECO:0000313|EMBL:PWK57644.1, ECO:0000313|Proteomes:UP000245390};
RN [1] {ECO:0000313|EMBL:PWK57644.1, ECO:0000313|Proteomes:UP000245390}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 103371 {ECO:0000313|EMBL:PWK57644.1,
RC ECO:0000313|Proteomes:UP000245390};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Member of the two-component regulatory system NtrB/NtrC,
CC which controls expression of the nitrogen-regulated (ntr) genes in
CC response to nitrogen limitation. Under conditions of nitrogen
CC limitation, NtrB autophosphorylates and transfers the phosphoryl group
CC to NtrC. In the presence of nitrogen, acts as a phosphatase that
CC dephosphorylates and inactivates NtrC. {ECO:0000256|ARBA:ARBA00037696}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWK57644.1}.
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DR EMBL; QGGV01000002; PWK57644.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316G9R8; -.
DR KEGG; salo:EF888_12710; -.
DR OrthoDB; 9789238at2; -.
DR Proteomes; UP000245390; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF16; SENSORY HISTIDINE KINASE_PHOSPHATASE NTRB; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000313|EMBL:PWK57644.1};
KW Nitrogen fixation {ECO:0000256|ARBA:ARBA00023231};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000245390};
KW Transferase {ECO:0000313|EMBL:PWK57644.1}.
FT DOMAIN 135..351
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 357 AA; 38496 MW; 5E19D1CBFA6BD7C8 CRC64;
MNVFLQNLWL SLPIPAFLID PGDVLVEANP AAESFLNSSA RSLRGTPVFD TLAIDAPLDD
NIGRVRSEQA SLFMNNVDVG GGNLAPVSCN IQIAPMSNMP GFVLMLMEPR VLADRLGRSL
SVKSAAKSAI GMAEMLAHEI KNPLAGITGA AQLLSMNLAP EDAELTDLIV SETRRILALL
EQVEQFGNLR PPARRAVNIH DLLDRARKSA AVGFAAHMTI AELYDPSLPS TFVDSDQMVQ
VFLNLLKNAA EASKGSPGQI TIRTFYDMSL RLRRKDKTAT LPLNVEIIDD GPGLPPEIAQ
DVFEPFVSGR ENGTGLGLAL VSKIISDHDG WVSVDSIPGR TVFRISLPVA PKQAEEQ
//
