ID A0A316GAZ9_9RHOB Unreviewed; 573 AA.
AC A0A316GAZ9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Transporter (CPA2 family) {ECO:0000313|EMBL:PWK58149.1};
GN ORFNames=C7455_11090 {ECO:0000313|EMBL:PWK58149.1};
OS Roseicyclus mahoneyensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseicyclus.
OX NCBI_TaxID=164332 {ECO:0000313|EMBL:PWK58149.1, ECO:0000313|Proteomes:UP000245708};
RN [1] {ECO:0000313|EMBL:PWK58149.1, ECO:0000313|Proteomes:UP000245708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16097 {ECO:0000313|EMBL:PWK58149.1,
RC ECO:0000313|Proteomes:UP000245708};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWK58149.1}.
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DR EMBL; QGGW01000010; PWK58149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316GAZ9; -.
DR Proteomes; UP000245708; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR42751:SF3; NA(+)_H(+) ANTIPORTER; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245708};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 58..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 416..545
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 573 AA; 60697 MW; FC8D402689F994FB CRC64;
MEMIAQSPFA EISTLLVMAA VIGFLGIILR QPLIVSFIAV GLIAGPSALD VVRSDEQIDL
LSELGIAVLL FLVGIKLDVK LIRSLGAVSL LTGLGQVAFT SVFGYLIGLA LGLGAVTSLY
VAVALTFSST IIIVKLLSDK REIDSLHGQI ALGFLIVQDL VVVLAMIVLS AIGIGAGEGG
HGGGSVPLVL ASGVAMVAMV VLFVRYVANP LTERLARAPE LLVIFAIAMA AMFAAIGDIV
GLGKEVGGLL AGVALASTPY RETIAARLAP LRDFLLLFFF IALGSALDLS LLGAHVTGAV
IFSLFVLIGN PLIVLVIMGA LGYRKRTGFL AGLTVAQISE FSLIFVAMGV SLGHVQEDAL
GLVTMVGLVT IAASTYMITY SHQIYAVFER FLWVFERNGT PREPSEAGAH RDDGHKVIIF
GLGRFGTAIG IRLQKRGVKV LGVDFNPQAA RRWRELGLAT EFGDATDPEF VAELPLRQAE
WIVSTVPIHP TGLSHEDTRT TLIQLTRMSG FRGRIAVASH HARDTEELFA SGADLVLEPF
QDAADRAVDL LCGAPEAERT EIPLLGSEEK DAS
//
