ID A0A316H465_9RHOB Unreviewed; 495 AA.
AC A0A316H465;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=argininosuccinate lyase {ECO:0000256|ARBA:ARBA00012338};
DE EC=4.3.2.1 {ECO:0000256|ARBA:ARBA00012338};
GN ORFNames=C7455_101379 {ECO:0000313|EMBL:PWK62353.1};
OS Roseicyclus mahoneyensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseicyclus.
OX NCBI_TaxID=164332 {ECO:0000313|EMBL:PWK62353.1, ECO:0000313|Proteomes:UP000245708};
RN [1] {ECO:0000313|EMBL:PWK62353.1, ECO:0000313|Proteomes:UP000245708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16097 {ECO:0000313|EMBL:PWK62353.1,
RC ECO:0000313|Proteomes:UP000245708};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2-(N(omega)-L-arginino)succinate = fumarate + L-arginine;
CC Xref=Rhea:RHEA:24020, ChEBI:CHEBI:29806, ChEBI:CHEBI:32682,
CC ChEBI:CHEBI:57472; EC=4.3.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000985};
CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine
CC from L-ornithine and carbamoyl phosphate: step 3/3.
CC {ECO:0000256|ARBA:ARBA00004941}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWK62353.1}.
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DR EMBL; QGGW01000001; PWK62353.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316H465; -.
DR OrthoDB; 9769623at2; -.
DR UniPathway; UPA00068; UER00114.
DR Proteomes; UP000245708; Unassembled WGS sequence.
DR GO; GO:0004056; F:argininosuccinate lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR CDD; cd01359; Argininosuccinate_lyase; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR InterPro; IPR029419; Arg_succ_lyase_C.
DR InterPro; IPR009049; Argininosuccinate_lyase.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR NCBIfam; TIGR00838; argH; 1.
DR PANTHER; PTHR43814; ARGININOSUCCINATE LYASE; 1.
DR PANTHER; PTHR43814:SF1; ARGININOSUCCINATE LYASE; 1.
DR Pfam; PF14698; ASL_C2; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00145; ARGSUCLYASE.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022571};
KW Arginine biosynthesis {ECO:0000256|ARBA:ARBA00022571};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:PWK62353.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245708}.
FT DOMAIN 51..299
FT /note="Fumarate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00206"
FT DOMAIN 364..404
FT /note="Argininosuccinate lyase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14698"
SQ SEQUENCE 495 AA; 53195 MW; C584C9B6BD4AC435 CRC64;
MTDTSVFPDP VYRDTVLAPL FEGVKTHFAD HMDAINRAHL VMLVETAILG REDGQAIAHA
LDAIAAETDP AALSYTGEHE DWFFLVEAEL KKRIGDLGGA LHTARSRNDM DHTQFKMALR
IRAEEALARL LRLAGALLDK ARAERDTLIV AYTHGQPAQP STFGHYLAAM IEVLLSDARR
FDAAIAPLDL CPMGAAAITT SGFPIDRARM ADLLGFTSAK VNAYGCIASV DYVTGLYSAL
KLPMIHLGRV VQDMAFWSAF EVGQLHVPRS LVQISSIMPQ KRNPVPIEHM RHIASVAAGR
CDVIVNTMHN TPFTDMNDSE GEVQQAGYGA FEHAARVLDL LTAFLPACSI NAERVAHTTD
AACITITELA DTLVRAEGLS FRQAHEIAAA TARAVIAAGS PLKQGYAPFA TAFAEVTGRP
PALTQAAFTD AVDARSFVTR RDRIGGPAPA ALDAAFADYD ATLDALSAAQ SARLARRAAA
ALRLDAAFQD LKGRP
//
