ID A0A316TCQ1_9ACTN Unreviewed; 1312 AA.
AC A0A316TCQ1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=ATP-dependent RNA helicase HrpA {ECO:0000313|EMBL:PWN02143.1};
GN Name=hrpA {ECO:0000313|EMBL:PWN02143.1};
GN ORFNames=DJ010_13500 {ECO:0000313|EMBL:PWN02143.1};
OS Nocardioides silvaticus.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=2201891 {ECO:0000313|EMBL:PWN02143.1, ECO:0000313|Proteomes:UP000245507};
RN [1] {ECO:0000313|EMBL:PWN02143.1, ECO:0000313|Proteomes:UP000245507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCTCC AB 2018079 {ECO:0000313|EMBL:PWN02143.1,
RC ECO:0000313|Proteomes:UP000245507};
RA Li C., Wang G.;
RT "Nocardioides silvaticus genome.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWN02143.1}.
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DR EMBL; QGDD01000006; PWN02143.1; -; Genomic_DNA.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000245507; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:PWN02143.1};
KW Hydrolase {ECO:0000313|EMBL:PWN02143.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245507}.
FT DOMAIN 32..201
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 236..415
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 446..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1312 AA; 146963 MW; 9F8EA76E5C11083C CRC64;
MAGSGRTREN ASAVNITYPP DLPVSARRDD IAKAINDHQV VIVAGETGSG KTTQLPKICL
ELGRGTPGDD GRPRMIGHTQ PRRIAARAVS ERIAEELGTE LGDLVGYQVR FTDRTSKTSR
VKVMTDGILL AELQRDRMLK RYDTIIIDEA HERSLNIDFL LGYLRQLLPK RPDLKLIITS
ATIDPERFAE HFSDKDGKPA PIVEVSGRTY PVEVRYRPLV ELPEEDEEGE PIVRDQTEAI
VEAVKELSAE GPGDVLVFLP GEREIRDTAE ALQGLDKLDH RGAVPGVDVL PLYSRLSAAE
QHRVFAPARD SRRRVVLATN VAETSLTVPG IRYVVDTGVA RISRYSSRTK VQRLPIEPIS
QASANQRSGR CGRVAAGIAI RLYSEEDFEG RPEFTDPEIL RTNLASVILQ MTSLGLGDVG
RFPFVEPPDR RNIQAGQQLL EELGALATSN DSSRHEGRFD RPRDRNQRLT KVGQRLARLP
IDPRLGRMLL EAERLGCVRD VLVIVAALSL QDPRERPGAD QPAEQARADQ AHARFKAEGS
DFLTWLNLWR YLKQQQRELS GSAFRRMCKR EYLHYLRVRE WQEFQSQLRQ VAKEMGLRIE
KGEGEPDADG IHQALLSGLL SHVGLLEERE KVSTGSTNKG RADRRRPGPR EYLGARGAKF
AIFPGSGLAR KNPQFLMAFE LVETGRLWAR QNAAIEPEWA ERLGAHLVKR TYSEPHWSQK
RQAVMARERV TLYGVPLVAD RLISFGKVDR ALAREIFIRH ALVYGEWSTR HQFFHDNRRL
LQQVEELEHR ARRRDLVVDE HTLFDFYDAR VGAEVVSGAH FDQWWKQARR ERPDLLTFDP
AMLTHDAAAE VTEQDYPEQW VGDGGLTFDL SYHFEPGAAD DGITVDVPVA VLNRVGDEDF
SWNVPGLREE LVTELLRSLP KQLRVNFVPA PNTARQFLAQ VPAGEESLLD ALERYLRSTT
GVHVPREAWD LGSLAPHLRP TYRVVDEKGR EQARGKDLTA LKAPLQPRFE KAMAEVAADS
GVARTGETSW VFGKIERTAT WTRAGHEVEA FPGLVDEGET VGLQVFGSAE ERDARHRLGL
VRLVLLGLDG DGRVDPNDLS NEEKLRLAGT SYSSVQALLA DCLRAVVVDA VDAAQQQEIL
RTQQEYDALL ASLRADAAGS VRALLPDLFR VLDGHRETDR LLSGRAELAL LPALSDMQAQ
LARLVPEGFV GEAGAAQLRR YPVYLAAIRR RREQLGEGGL AVARDRDRLD RVQPLQEAYL
HRIEALPAGR PPGSALRQVR WQLEEFRVSL WAPQLGTAGK VSDVRIRKLL EA
//
