ID A0A316UHS7_9BASI Unreviewed; 1276 AA.
AC A0A316UHS7;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Putative SKI2-antiviral protein and putative helicase {ECO:0000313|EMBL:PWN23483.1};
GN ORFNames=BCV69DRAFT_264609 {ECO:0000313|EMBL:PWN23483.1};
OS Pseudomicrostroma glucosiphilum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Exobasidiomycetes; Microstromatales; Microstromatales incertae sedis;
OC Pseudomicrostroma.
OX NCBI_TaxID=1684307 {ECO:0000313|EMBL:PWN23483.1, ECO:0000313|Proteomes:UP000245942};
RN [1] {ECO:0000313|EMBL:PWN23483.1, ECO:0000313|Proteomes:UP000245942}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 4718 {ECO:0000313|EMBL:PWN23483.1,
RC ECO:0000313|Proteomes:UP000245942};
RX PubMed=29771364; DOI=10.1093/molbev/msy072;
RA Kijpornyongpan T., Mondo S.J., Barry K., Sandor L., Lee J., Lipzen A.,
RA Pangilinan J., LaButti K., Hainaut M., Henrissat B., Grigoriev I.V.,
RA Spatafora J.W., Aime M.C.;
RT "Broad genomic sampling reveals a smut pathogenic ancestry of the fungal
RT clade Ustilaginomycotina.";
RL Mol. Biol. Evol. 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
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DR EMBL; KZ819321; PWN23483.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316UHS7; -.
DR STRING; 1684307.A0A316UHS7; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000245942; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR040801; Ski2_N.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:PWN23483.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245942};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 326..484
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 608..804
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 192..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1276 AA; 142331 MW; 13D0958B2C02E114 CRC64;
MASSSSSSKP HHDRLARLQA QLKELRLAPS SELVGSRYSR NEIKEMLQKR FTATHNRIEQ
PGLDELQVHW RRTPDLKSLL PSDPLPQTTS LRFIRAGLDG HIIGSQEVVT HQPASSSAVA
RKTQLELRKL AATQRKGMSF VRGRSGGTMF MPGGLDDDDL ALEPEGEVDG VEAEVKQVEA
AIKDWGRGLR TIPPGFERGF RAPGQGEEDE EDEADLMDDD ASKGLVAAPV YQPSLKQPAS
LKVSGAPEPP SSNEATNELD ELLPTDKPHT GAEASSSRSK GRQDIEKREW AHVVDSSKRL
ANFDQLIPHP AHKFPFTLDP FQQEAVYHLE QGDSVFVAAH TSAGKTVVAE YAIALAQKHM
TRCIYTSPIK ALSNQKYRDF KTTFGAENVG ILTGDVQINP EAPCLIMTTE ILRSMLYRGA
DLIRDVEFVI FDEVHYVNDQ ERGVVWEEVI ILCPQHISLI LLSATVPNTR EFADWVGRTK
KKDIYVISTS KRPVPLEHFL YANRDIFKVV DASSRFLESG IKEAGDALKR KQDKEREAAG
IAQPVRQGAR GGSAGGSNAR GGRGGGGVQR GGLVARGGTP AQRGRGGAAS MARTMGGDTK
NLYVHLTGLL KKKDLLPVVI FVFSKRRCEE YASSIPNTDL CTAKEKSEVH IVIERSLMRL
KGSDRQLPQI QRMRELLGRG VAVHHGGLLP IVKEIVELLF QRGLVKVLFA TETFAMGVNM
PARSVVFSGI RKHDGHSFRE LLAGEYTQMS GRAGRRGLDK TGVVIINAAE ELPETAILHK
MLLGQPTKLQ SQFRLTYNMI LNLLRVETLK VEEMIKRSFS ENASQRLLPD QQKKVEERKK
KLERLPRVQP PEREEELRRY HDAARAVGVA FHGVLELALE QQQGSKIFAP GRVVLLRDAH
FNNNPAVLVK QVASRIFLVL AAVSPRRKKG EYDLEDDSQV APRWPPVMST EGEEELVYDL
REVPLQSLSL VTKHTLKIDQ SMIMAHRISA MNKTVEAMQG TIVELRAAGE RAASSQEVEW
SKLRRLDFQE SLKSRDDRAR TVAPIEEGEN FAKEYRITHA RKGLEREIAR IEHSMSNQNL
ELLPDYEQRV EVLKTLRFID PLTESVLLKG RVACEINSAD ELVLTELILD NVFATYTPAE
IVALLSVFVF QEKSDSEPVL TERLQEGLAT ILSTSERVSQ VQAEHQLNYN DYSTSLKIGL
VEVVHRWAEG TSFEEITQLT DVAEGTIVRV MTRLDQTCLE VRDAARVIGD GQLKEKMEEA
QVMIRRDILA APSLYF
//
