ID A0A316VPB4_9BASI Unreviewed; 733 AA.
AC A0A316VPB4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=tRNA (guanine(26)-N(2))-dimethyltransferase {ECO:0000256|ARBA:ARBA00039099};
DE EC=2.1.1.216 {ECO:0000256|ARBA:ARBA00039099};
GN ORFNames=IE81DRAFT_326820 {ECO:0000313|EMBL:PWN39154.1};
OS Ceraceosorus guamensis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Exobasidiomycetes; Ceraceosorales; Ceraceosoraceae; Ceraceosorus.
OX NCBI_TaxID=1522189 {ECO:0000313|EMBL:PWN39154.1, ECO:0000313|Proteomes:UP000245783};
RN [1] {ECO:0000313|EMBL:PWN39154.1, ECO:0000313|Proteomes:UP000245783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 4658 {ECO:0000313|EMBL:PWN39154.1,
RC ECO:0000313|Proteomes:UP000245783};
RX PubMed=29771364; DOI=10.1093/molbev/msy072;
RA Kijpornyongpan T., Mondo S.J., Barry K., Sandor L., Lee J., Lipzen A.,
RA Pangilinan J., LaButti K., Hainaut M., Henrissat B., Grigoriev I.V.,
RA Spatafora J.W., Aime M.C.;
RT "Broad genomic sampling reveals a smut pathogenic ancestry of the fungal
RT clade Ustilaginomycotina.";
RL Mol. Biol. Evol. 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Trm1 family. {ECO:0000256|PROSITE-ProRule:PRU00958}.
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DR EMBL; KZ819490; PWN39154.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316VPB4; -.
DR STRING; 1522189.A0A316VPB4; -.
DR InParanoid; A0A316VPB4; -.
DR OrthoDB; 942596at2759; -.
DR Proteomes; UP000245783; Unassembled WGS sequence.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR Gene3D; 3.30.56.70; N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002905; Trm1.
DR InterPro; IPR042296; tRNA_met_Trm1_C.
DR PANTHER; PTHR10631; N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10631:SF3; TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE; 1.
DR Pfam; PF02005; TRM; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51626; SAM_MT_TRM1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Reference proteome {ECO:0000313|Proteomes:UP000245783};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00958};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00958};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; tRNA processing {ECO:0000256|PROSITE-ProRule:PRU00958};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555, ECO:0000256|PROSITE-
KW ProRule:PRU00958}.
FT REGION 91..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 78241 MW; FE848BF616F2E895 CRC64;
MFPRRISTVC ASSFLSLQRP ALNLTMAPTP VALSTSAAAA LGISSDQSAF KEGSAVISIP
KSDAAFLNPV QEFNRDLSVL AIRTWAERRD REKREKFEQA ISKRKERSAN GRGKRRKIAH
TATSNASDAA SLDNASSTSA KRADLSASAS STAAATAAGD VSTASTSSHA HIDSSHRPFT
FNIFEALSAT GLRSIRYARE IPNLKSVHAN DLSPTAVQAI WKNVALNFPA NRDIKQWAPE
LDRGEPEKDD AEASSTAEAA AAAARSASSS EAASAQFASN GAANGAGHPA IHPKCKIHVT
EQDAIEILYT SRAKDKQYSV IDLDPYGSAS MFIDGAVQAV ADGGLLCVTC TDLVVLAGNA
YPERAYSLYG GTTTRNDFVH EVALRLVLGL IATTAGRYGR AITPLLSLSI DFYLRVFVSV
HTRPVDVKML ASTMGTVQTC PDCGNWDANA FGRNKAEGRA DLIKYQAGTS HTVGTNCQEC
DSRFHVAGPM WLGPLHTPSF AEEMLEVLER APVRFRTAPR IRGMVGMASK ELSSPFFFIP
PKISSYFHTT NIPLTAVVSC LLNAGYEVSR SHAQPASIKT NASPTVVRDL WRQWVKEKSP
INEKNVHENS PARRLLAKEC ATTFELDKDH PQTRQVLGLD QDGKKNAGVK YQLNPLPNWG
PGKAARPESK KDRKRAAAAA AAAAASSESN GTGGGRANVS GLAASAGVDA SAQGDVQANN
QAASMDEDEL RNS
//
