ID A0A316YFU2_9BASI Unreviewed; 574 AA.
AC A0A316YFU2;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=MATE efflux family protein {ECO:0000313|EMBL:PWN87946.1};
GN ORFNames=FA10DRAFT_234097 {ECO:0000313|EMBL:PWN87946.1};
OS Acaromyces ingoldii.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Exobasidiomycetes; Exobasidiales; Cryptobasidiaceae; Acaromyces.
OX NCBI_TaxID=215250 {ECO:0000313|EMBL:PWN87946.1, ECO:0000313|Proteomes:UP000245768};
RN [1] {ECO:0000313|EMBL:PWN87946.1, ECO:0000313|Proteomes:UP000245768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 4198 {ECO:0000313|EMBL:PWN87946.1,
RC ECO:0000313|Proteomes:UP000245768};
RX PubMed=29771364; DOI=10.1093/molbev/msy072;
RA Kijpornyongpan T., Mondo S.J., Barry K., Sandor L., Lee J., Lipzen A.,
RA Pangilinan J., LaButti K., Hainaut M., Henrissat B., Grigoriev I.V.,
RA Spatafora J.W., Aime M.C.;
RT "Broad genomic sampling reveals a smut pathogenic ancestry of the fungal
RT clade Ustilaginomycotina.";
RL Mol. Biol. Evol. 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199}.
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DR EMBL; KZ819639; PWN87946.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316YFU2; -.
DR STRING; 215250.A0A316YFU2; -.
DR InParanoid; A0A316YFU2; -.
DR OrthoDB; 661905at2759; -.
DR Proteomes; UP000245768; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206:SF153; ETHIONINE RESISTANCE-CONFERRING PROTEIN 1; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245768};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 194..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 60123 MW; A9A22AF70CCA234C CRC64;
MPRHQSAGWL TPAAHHEGAS SSSPLADAAR ETSPLLQAGA HSGYGGTATA SISTGASTGN
GHHNHTVHRR PSLVGGAASG WDRTAPGLPG QETLDELAHE AAQQPGPRRE LAVLLAYSAP
IWATHVLELS LNVVSVFSLG HLGTTELAAA SLSSMTANVT GFSVLSGFIS ALDSVLPAAY
SHAPKTVGLW TQRAAVISAV LLVPISAIWL ASEQILGLLG QEEQVAALAS LYLRILVLGL
PGYACFEICR RYLQAQGLMH APTVVLFVAS PLNAVLNYLL VWGPPSVRLG FIGAPIASVV
STWLMALLCL LQCYVAPRIA WAGWSRRAFS GLSPLVNLGL AGTLAICSEW WSWEIVGLVT
TRLGTVALAA QSVLLVSSSI TYQLPFALSV AAAVRVGNHL GAGQAHAANV ASNMSMLLSL
ACGAFNSALF LAFRNQWGYW FTEDRAVIDL VYAILPLLAL FQVADGICGV AGGVLRGTGR
QAQGAVANLV GYYLIGIPLG FFLTFGPWQW GLAGLWIGLT VALLFASLAM GLVLGCTDWR
YEVHKTFVRM GVDDDGPTPK PASNHAPAAA PAEP
//
