ID A0A316Z1X7_9BASI Unreviewed; 943 AA.
AC A0A316Z1X7;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
GN ORFNames=FA09DRAFT_301232 {ECO:0000313|EMBL:PWN95559.1};
OS Tilletiopsis washingtonensis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Exobasidiomycetes; Entylomatales; Entylomatales incertae sedis;
OC Tilletiopsis.
OX NCBI_TaxID=58919 {ECO:0000313|EMBL:PWN95559.1, ECO:0000313|Proteomes:UP000245946};
RN [1] {ECO:0000313|EMBL:PWN95559.1, ECO:0000313|Proteomes:UP000245946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 4186 {ECO:0000313|EMBL:PWN95559.1,
RC ECO:0000313|Proteomes:UP000245946};
RX PubMed=29771364; DOI=10.1093/molbev/msy072;
RA Kijpornyongpan T., Mondo S.J., Barry K., Sandor L., Lee J., Lipzen A.,
RA Pangilinan J., LaButti K., Hainaut M., Henrissat B., Grigoriev I.V.,
RA Spatafora J.W., Aime M.C.;
RT "Broad genomic sampling reveals a smut pathogenic ancestry of the fungal
RT clade Ustilaginomycotina.";
RL Mol. Biol. Evol. 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|RuleBase:RU361221}.
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DR EMBL; KZ819303; PWN95559.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A316Z1X7; -.
DR STRING; 58919.A0A316Z1X7; -.
DR OrthoDB; 150430at2759; -.
DR Proteomes; UP000245946; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd03684; ClC_3_like; 1.
DR Gene3D; 3.10.580.20; -; 1.
DR Gene3D; 3.90.1280.20; -; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR45711:SF9; ANION_PROTON EXCHANGE TRANSPORTER GEF1; 1.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Chloride {ECO:0000256|ARBA:ARBA00023214, ECO:0000256|RuleBase:RU361221};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000245946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 240..258
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 278..295
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 307..331
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 384..404
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 416..437
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 474..494
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 506..527
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 548..572
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 578..599
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 782..838
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 31..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 903..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..763
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..943
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 943 AA; 100917 MW; 0BADA551154C5198 CRC64;
MDERALDEIR RYESFSTVDW IADSTRERAR VARQHASPGP GASPLDTGWG GRGGERPPRW
WPSSGPWGRI VWAVWLLVRK AAKGVEESAV VIGVGALIGL NMAVISIATE WASDLKTGYC
TAGWWLNRKF CCWEFMEGGG PGGTSPIPSS LKPSGGAGNA TMLARAGEAL EWGMALVPRA
EVQPGSSSEA CSDWQPWSSW TVVSWVIYVV FAAIFAALCS HLVRSFAPYA AGSGISEIKC
ILAGFIINGF LGTWTFAVKS LTLPLAIASG LSVGKEGPAV HVACCIGNVV ASFVKSFDRS
QARMRELLTA ASAAGVAVAF GSPIGGVLFS LEEMAYNFPA STMWRSFLCA LASTVTLSFM
NPFRTGKLVL FQVSYDRDWH YFEMFFYSII GVFGGLYGAF IIKYNLQVQR FRRDNLAAHG
VAEAIVLATL TAFVGYWNKF LRIDMSESLE ILFHECEGGG DYDSLCQSSA QWRMVNSLLI
ATVLRAALVV LSYGCKVPAG IFVPSMAIGA TFGRMVGILV KALYTAFPHA SIFSACQPDV
PCITPGTYAF LGAAAALAGV TRITVAVVVI MFELTGALTY ILPTMFVVMI TKGVGDLYGK
GGISDQTIRF QGYPFLDKDE HVFGLPVADI MTRGPAVLYG AGMPLAEVEQ RLASGPYKGL
PVVRSAEDPT LLGYAGKTEM RYAIAKARRA RSTLAPTTLC CFTSEADNDE ASGLGVHPLA
QHPPTPIVST FETMEPNNGK DDEHQGLMGG QDSDDEHDSL GEAGGGIDGE GDDDVLELGG
WMEQTPLCVQ PSMPLEVVMD LFKKMGPRVI IVTRLGRVVG LVTVKDVLKH HAATEHAAAV
AASAARDVRS GPGLPSAAAV PQDGFGGDLE LALSDLYTWF LTYARTLAPI AAKVRGWFPA
NGAGRSAARP QAPPGYSRPS RQAEAADEDE QREQFVLAGE GDE
//
