ID A0A317C1V9_9GAMM Unreviewed; 1457 AA.
AC A0A317C1V9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=DKW60_21625 {ECO:0000313|EMBL:PWQ92347.1};
OS Leucothrix pacifica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Thiotrichaceae; Leucothrix.
OX NCBI_TaxID=1247513 {ECO:0000313|EMBL:PWQ92347.1, ECO:0000313|Proteomes:UP000245539};
RN [1] {ECO:0000313|EMBL:PWQ92347.1, ECO:0000313|Proteomes:UP000245539}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 18388 {ECO:0000313|EMBL:PWQ92347.1,
RC ECO:0000313|Proteomes:UP000245539};
RA Choi A., Baek K.;
RT "Leucothrix arctica sp. nov., isolated from Arctic seawater.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWQ92347.1}.
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DR EMBL; QGKM01000095; PWQ92347.1; -; Genomic_DNA.
DR OrthoDB; 5618688at2; -.
DR Proteomes; UP000245539; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR024983; CHAT_dom.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF12770; CHAT; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00255; TIR; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50104; TIR; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000245539};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 4..126
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REPEAT 1216..1249
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 1457 AA; 163107 MW; 83F1E95D05D7F8F5 CRC64;
MPIESGHVFI SHTSADDEFV KALRIKLELH GISLWVDSRN LCGGKKLAPE IEQAILDSSH
VIAVLSPRTI NSPWVRKEIQ FAEDKGHDVI PLLLPGIEPS ALGMWFDEEP VGEKIELDVG
KLDEQLPHIL AALGKRAPDH DLAKAQEVAN KPIAELLLEL TEPTLTHGEY GIETLSARAE
IRYIPPDLSK EREVNSRTFR FTAPIGQIEQ DEIRWYLEQY LQWPVGLFRE RAKTTEAQLP
EWGKALYNAT LGQAVCREPV TAWQQARGDV ERRFSVQVDA HTLETDEDAQ ANANEAASRL
QSLPWELLHD DAYLSDGANP VRIRRRLPNF KHQPPSSAEL PIRILLLSPR PEEQGVGYID
HRASALPLVQ AVETLGDLVR LTVLSPPTLP ALEKELHRAR EAKKPYHVLH FDGHGVYDRQ
FGLGALCFEH PQDDALLEGR RSQLVYAKAS QNSASTNQTS APPQSNLVSL LKDFRIPLVF
LEACQTAQTE ADPNTSVAAS LLDEGVTSVV AMSHSVLMET ARLFVTEFYQ SLALGQRVGA
AMLAGQKKLM RDSYRLPIPG AGDLHLQDWF VPILYQEQHD PQLFAWVPSE TAQKMQAQQR
QTRLGRLPEP PPHHFIGRSR DLLKAERLLE QQPYAVIRGQ GGAGKTTLAV ELAKWLVNSR
RFDRCAFVSV EEYTHDRAVT EVLLQQLVNA NHNLVVEYDG DIDQALQTIR RTLENDRTLI
VVDNMESLLA DDANKQAVLD VLAKLPEAKL LFTTRESLPE PFHHKVREIE LGTLELSDAK
ALVMQVMNQE GLSLRHDDTG NTPQEVNDLV NSVGCHARAL VLLARELAQR GVTATTNNVR
EIMQDLEQRY PGQRENSLFA SVELSLQRLS PEVLEQIAGL TVFQDGGHIT SIAHVLEVDS
EQITLIIQEL FDVGLATSIG EYNYICLDPA LPAYLNLSLN TEQYETYQQR WQEVMGQLVD
SLHGQISKDS KLIFNLVPLE LPNLMAYLQV LVSSWQAGTQ MAEVVSDKVC SVEKLLENLN
QPHAIAKVME WRELVATVFV EWSHARFDNE HLSIEQRLKE GDFPSAIQAA QALLKQCQQA
GEKSYIGAGY DFASANFLLG RVLRTSGAEE KALPYLQEAQ QRFEAIGVRG ERMVSVALTE
RGSCLERLGQ LDAAEMLYEK SIIQQGENKG NTHGVALGKQ RIATIRWLQK RHSDAVLGFQ
QALELFMQLG DLLAAASVWH KIGMCYTDSR DFEEAEKAYQ QSISINNQKG NKVGEAENLS
ELGNLYNYWG RSEQALIYDR RGADIYEDLG HFLQEGVARN NVADTLIKLS RYDEAREELL
LAIKCQQGFG HSGKPWNTWS TLHSLEKVSG NLQAASDAWQ KALLAYLVYR RDGGDGHDGS
GRLTLAVGVA IKKDNTSQIE QMIGQLSERV DWRGHKNFLQ KLQAIIAGKR DLALAEDEGL
YYQYAAELII LLESLAE
//
