ID   A0A317EAL9_9PROT        Unreviewed;       816 AA.
AC   A0A317EAL9;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Homospermidine synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DKG75_01515 {ECO:0000313|EMBL:PWR23276.1};
OS   Zavarzinia compransoris.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Zavarziniaceae; Zavarzinia.
OX   NCBI_TaxID=1264899 {ECO:0000313|EMBL:PWR23276.1, ECO:0000313|Proteomes:UP000246077};
RN   [1] {ECO:0000313|Proteomes:UP000246077}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1231 {ECO:0000313|Proteomes:UP000246077};
RA   Lee Y., Jeon C.O.;
RT   "Zavarzinia sp. HR-AS.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWR23276.1}.
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DR   EMBL; QGLF01000001; PWR23276.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A317EAL9; -.
DR   OrthoDB; 9767495at2; -.
DR   Proteomes; UP000246077; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.360.30; homospermidine synthase like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR023181; Homospermid_syn-like_C.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   InterPro; IPR017039; Virul_fac_BrkB.
DR   NCBIfam; TIGR00765; yihY_not_rbn; 1.
DR   PANTHER; PTHR30213:SF0; RIBONUCLEASE-LIKE PROTEIN YFKH-RELATED; 1.
DR   PANTHER; PTHR30213; UNCHARACTERIZED; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   Pfam; PF03631; Virul_fac_BrkB; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000246077};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        171..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        214..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        354..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          359..497
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          501..766
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   816 AA;  88396 MW;  49CAF60EC12F260B CRC64;
     MADVEIEAGA PAGATPVPPS SSARLGPLMR LVLAPVFMVG RIFKALFRAL LRASREDATN
     LAAYLSFTGL LSLFPFLIAL AALAGSLGTA NSAQQAVQAL FTFLPEDVAK TLAPAVRQVL
     LSGQKSDLLT IGVVVTLFTA GNGIAALRVA LNRAYGAVEH RHFLVQQAIH LSLVLLGAVV
     MIGISFAVIL GPQVWDWLVK PYAPRSWSRP LWDFARYGTG TLMVFASLVF MHWALPARRL
     KIRLVLAGSA LTTLGWIACA SLFSLFLRNV GNYNVTYGSL GSIVVVLVFF YASATLLLIG
     AHFNVALFSI EPASPPSPQP NLSMGAIRER GLRALRSVFR RTMTMDRQTQ HTAFAGRLVI
     IGFGSIGQGV LPLILRHIDM PADRITIVTA EEQGAAVAAE YGVTFIKEPL TRDNYASLLT
     PLIGRGDFIL NLSVDVSSLA LVEFAHGRDA LYLDTCIEPW AGGYTDTSLS ASARSNYGLR
     EQALALKAKY PGGPTAVLTH GANPGHVSHL VKQGLLDIAA ASNHPAAVPT SREGWAALAR
     DLGIKVIHIA ERDSQKANIP RAIGEFVNTW SIDGFVGEGC QPAELGWGTH ERHFPADGAR
     HDYGAGAAIY LKRPGASVRI RTWTPMEGPF HGFLITHSEA ISLADYLSVS ENGETVYRPT
     SHYAYHPSDD AVMSVHELAG KNWKMQDRKR LMRDEIVSGY DELGVLLAGH AKGAYWLGSH
     LDIHTARTLA PHNGATTLQV TSSVLAGLVW AIENPRKGVI EPEEMDFARC LAIAGEYWGP
     RVGVFTDWTP LDDRAQLFEE DLDTEDPWQF KNIRVI
//