ID A0A317FK69_9PROT Unreviewed; 910 AA.
AC A0A317FK69;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|ARBA:ARBA00021982};
GN ORFNames=DFH01_05730 {ECO:0000313|EMBL:PWS38752.1};
OS Falsiroseomonas bella.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Falsiroseomonas.
OX NCBI_TaxID=2184016 {ECO:0000313|EMBL:PWS38752.1, ECO:0000313|Proteomes:UP000245765};
RN [1] {ECO:0000313|Proteomes:UP000245765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQN31 {ECO:0000313|Proteomes:UP000245765};
RA Du Z., Wang X.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|ARBA:ARBA00024647}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWS38752.1}.
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DR EMBL; QGNA01000001; PWS38752.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317FK69; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000245765; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 6.10.140.430; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 3.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756};
KW Reference proteome {ECO:0000313|Proteomes:UP000245765}.
FT DOMAIN 720..736
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 910 AA; 95932 MW; 5EF44533CF79D0BE CRC64;
MDRPSPSPPA AGDRIPRAEG ATPAMAQWFA AKAAHPDALV FFRMGDFFEL FFCDAEDAAP
VLDIAVSHRG EHRGQPVPMA GVPAHALDAY LARLIRAGWR VAICDQMETP EEAKRRKAAT
IRREVVRVVT PATVTEDGLL DASRPAWLLA VAPGEDGFGA AWLDISTGGF CTATLPRAEL
GALLARLEPA EAVTAPELSE DTELAQRLPG RIAPRLVPRD AARLVREAYG VATLDGFGRF
APAELDAAAL AIGYVRETQA GLLPRLDPPR PQTDAAGVLA LDAATRRSLE ILRDQRGGTE
ATLLAAVDRT LTAAGARELA ARLAAPLAEA APIAARHDAV AFLLGDAALR GAIRAALKGA
PDMARALARL ALDRFAPRDL GALRAGLDLA AHLVATLAAP ALPVPKLVAE AAAALRLDPS
LSAELGRALS EKLPARLEDG GIIAAGYDGE LDALRRLRDG GREAIAALQL DLAQAWGVAS
LKIRHHQQFG FLAELPAAPA EKLLRDPPKG LSPEHAPIHR QTMANAVRFT CTALAELDRK
VAEAGTRAAE RERACVKHLR RLLLDAGGPI AEAARAIAEL DLHAAAAALA EEGGWCRPEI
TDRPDFAIAG GRHPVVEAAL RKARGPAFVP NDCDLSPGRR LCLLTGPNMA GKSTWLRQNA
LIVVLAQAGL FVPATSARLG LVDRLFSRVG GGDDIAGGRS TFMVEMAETA AILNGATPRS
LVVLDEVGRG TATWDGLAIA WSVLEALHDR IRCRAIFATH FHELTALAGR LPELRLGQMQ
VAEWRGEVVF RHQVGDGAAQ KSWGVHVARL AGVPRAVLAR ANQVLNALEA RARAGGPDAL
AEELPLFARP AAAAPAPPPS PLHAALAGLD PDALSPREAQ EALYRLKALV AEDAATQHDD
TVAGGRESVS
//
