ID   A0A317L4F1_9BACI        Unreviewed;       214 AA.
AC   A0A317L4F1;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=Steroid 5-alpha reductase C-terminal domain-containing protein {ECO:0000259|PROSITE:PS50244};
GN   ORFNames=DLJ74_00755 {ECO:0000313|EMBL:PWU70396.1};
OS   Gracilibacillus dipsosauri.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Gracilibacillus.
OX   NCBI_TaxID=178340 {ECO:0000313|EMBL:PWU70396.1, ECO:0000313|Proteomes:UP000245624};
RN   [1] {ECO:0000313|EMBL:PWU70396.1, ECO:0000313|Proteomes:UP000245624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DD1 {ECO:0000313|EMBL:PWU70396.1,
RC   ECO:0000313|Proteomes:UP000245624};
RA   Deutch C.E., Yang S.;
RT   "Genomic analysis of Gracilibacillus dipsosauri DD1 reveals novel features
RT   of a salt-tolerant amylase.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWU70396.1}.
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DR   EMBL; QGTD01000001; PWU70396.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A317L4F1; -.
DR   OrthoDB; 9779233at2; -.
DR   Proteomes; UP000245624; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1630; -; 1.
DR   InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR   InterPro; IPR010721; UstE-like.
DR   PANTHER; PTHR32251; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR   PANTHER; PTHR32251:SF15; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295); 1.
DR   Pfam; PF06966; DUF1295; 1.
DR   PROSITE; PS50244; S5A_REDUCTASE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245624};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        135..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        166..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          104..184
FT                   /note="Steroid 5-alpha reductase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50244"
SQ   SEQUENCE   214 AA;  24633 MW;  93E30D57FABBCC5E CRC64;
     MYGIQKQSTK QKSFILIAQI VYLIIAYYVL FSLNEENFLS IGLFTALFIT SLRLNAMMFL
     WLPRGIGWME AIGNSLAFAL YYLGFPLLAI ANDNDASMTL FMVGWIIFLL GSFINTGSEL
     LRKTFKDNPE NKGKLYTGGL FHYAIHINYF GDCLWVLGLA ILTNNFFSLF IPLGLLLLFV
     TSYIPNHDKY LQDKYGDQFI EYKKSTKKLI PFIW
//