ID A0A317SDC5_9PEZI Unreviewed; 624 AA.
AC A0A317SDC5;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=VHS-domain-containing protein {ECO:0000313|EMBL:PWW72148.1};
GN ORFNames=C7212DRAFT_287283 {ECO:0000313|EMBL:PWW72148.1};
OS Tuber magnatum (white Piedmont truffle).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Tuberaceae; Tuber.
OX NCBI_TaxID=42249 {ECO:0000313|EMBL:PWW72148.1, ECO:0000313|Proteomes:UP000246991};
RN [1] {ECO:0000313|EMBL:PWW72148.1, ECO:0000313|Proteomes:UP000246991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=091103-1 {ECO:0000313|EMBL:PWW72148.1};
RA Murat C., Payen T., Noel B., Kuo A., Martin F.M.;
RT "Genomes of Pezizomycetes fungi and the evolution of truffles.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWW72148.1}.
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DR EMBL; PYWC01000117; PWW72148.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317SDC5; -.
DR STRING; 42249.A0A317SDC5; -.
DR Proteomes; UP000246991; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0016482; P:cytosolic transport; IEA:UniProt.
DR GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14235; GAT_GGA_fungi; 1.
DR CDD; cd16998; VHS_GGA_fungi; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.60.40.1230; -; 1.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR008153; GAE_dom.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47180; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR PANTHER; PTHR47180:SF1; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50180; GAE; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000246991};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 26..162
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 189..316
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT DOMAIN 502..622
FT /note="GAE"
FT /evidence="ECO:0000259|PROSITE:PS50180"
FT REGION 404..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 624 AA; 68044 MW; 7D7A05121F2C08A2 CRC64;
MAARDRFGAF PQEPNGSKLQ RFIQSACDPV NYEPNLALNL EIADEINKRK GNAPREAAVA
IVNYINHRNN NVSLLALNLL DICVKNCGYP FHLQISTKDF LNELVRRFPE RPPARPSRVH
LKILEAIEEW RGTICQTSRY KDDLGFIRDM HRLLSYKGYV FPEVRREDAA VLNPSDTLKS
AEEMEEEERA AQSAKLQELI RRGTPADLQE ANHLMKIMAG YDQTSRTDYR AKAAEEIGKL
REKARLLEEM LGKVHKGETI GQQDTFEELA NALRTAQPKI QKIIEEESED PDAVVKLLEL
NDVINTTVER YNFVKRGDLD SAKALPLMAG ASPSTAPPPP AVELSLIDLE DSANGGPSAP
ASGKPASLEE DLLGLSFQDS GNGSFGQGGG IALGFGANTG IPGPPLLSST LETNTAGQQQ
HITPSTSPAP HISRQPPALP NYFQNVASSS TQPMAPGGFV PPSIQQTPVP PAQQNNGGSA
DNDDDDWAFT SSLPPEQPAP PPVSQNELVI LNSNLHILLD IHRPVTMPDG PILVKAKFSN
NASQPIQDLT FQMAVTRTLA LRMEPQSSRH LEARQRAGVT QIIRVSGVPR GGGGNVKLRW
KASYRVGTGP LNEEQGVIES LPVA
//
