ID A0A317SH22_9PEZI Unreviewed; 1699 AA.
AC A0A317SH22;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Vacuolar import and degradation protein 21 {ECO:0000256|ARBA:ARBA00029670};
GN ORFNames=C7212DRAFT_365973 {ECO:0000313|EMBL:PWW73713.1};
OS Tuber magnatum (white Piedmont truffle).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Tuberaceae; Tuber.
OX NCBI_TaxID=42249 {ECO:0000313|EMBL:PWW73713.1, ECO:0000313|Proteomes:UP000246991};
RN [1] {ECO:0000313|EMBL:PWW73713.1, ECO:0000313|Proteomes:UP000246991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=091103-1 {ECO:0000313|EMBL:PWW73713.1};
RA Murat C., Payen T., Noel B., Kuo A., Martin F.M.;
RT "Genomes of Pezizomycetes fungi and the evolution of truffles.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC is involved in transcriptional activation of selected genes principally
CC by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. {ECO:0000256|ARBA:ARBA00025178}.
CC -!- SIMILARITY: Belongs to the EAF1 family.
CC {ECO:0000256|ARBA:ARBA00008913}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWW73713.1}.
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DR EMBL; PYWC01000075; PWW73713.1; -; Genomic_DNA.
DR STRING; 42249.A0A317SH22; -.
DR Proteomes; UP000246991; Unassembled WGS sequence.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:UniProt.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR014012; HSA_dom.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR46459:SF1; E1A-BINDING PROTEIN P400; 1.
DR PANTHER; PTHR46459; E1A-BINDING PROTEIN P400-RELATED; 1.
DR Pfam; PF07529; HSA; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR SMART; SM00573; HSA; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51204; HSA; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000246991}.
FT DOMAIN 919..1001
FT /note="HSA"
FT /evidence="ECO:0000259|PROSITE:PS51204"
FT DOMAIN 1214..1266
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 133..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1115..1154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1617..1699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1617..1637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1666..1682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1683..1699
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1699 AA; 185901 MW; 6A6891C38CB474DB CRC64;
MVEKISIQNL RNNALSTRLE ERKNIVISRK RKLQEVYAVC RHIDRTKPFP NADIVETWGT
IERYGGANME DGEKRFLDEN DIERGRLFQE STLPPHSSYL PEPGGFQKTF AAQLTPHHGV
KAISRHATPL SASVPEKPVQ ALEHPAVSRE PELLTEKEAR HAFDVRNRME DQSPTKSGVT
NGKRSSEAPT EDGSVDSEAT EEDLGSLSHI TEPNERVKLG NAAPVVGIGG VPVVQEAATR
VPDDHERSLG VRPPPIPSEL VDAARGKATQ IAAVRDGKTR ERDTRVEKAK STEPVTVTSF
GDSVREVPDS FESSQVSSLS EPPSPATSKG TILELGEEPR LPVASPEIQH IPPQPPLVII
TNKENRPAPI PPSKSPSRHA SHSDVCSPTS SVDGDNRSTP GNILSSATSP DANHMLGPDP
RSEERNGQIK EVVAESGPYG VRTMPAKEAE EEELAGTFVE GKVVPCGVQS ERSLPSVIVA
AEFVMDEEGT QSQLPTTPPP ELTNGGEPDL AAVEAGVAIT LPKADEAQSA RTNKSTSPDP
SAQLRLENSL AQDDIEPDSL ANEGPHSSQK LTGVGETHDE DLEDRVQLVG SGEPEPRAAG
PAREVAEVVR EVKHASENME IDIPDKVGDM EAAGHDTAMS GVDQSAVHGA TSGMHVGDIS
IGTISLPEQQ SLEVSTLQEI DDSKMEVDHT ANEQHDETGL PGKAPTPDVN TLVDATVEPP
GSPANSMFEP DNEEEVPSSG GMVVGGAESE GSLIPSTSPV KQPLRRRETR KKQAKLSKVV
ISSTHHALAA LEEEAKRLHE DQIAQGPIVV ARRRDQQAAS AAARRSAVFQ PGSKIDAITR
YGITEPPSEE KSKVKNADMF DIAYTAKASG TLISDLLQRS SKTLTTGDHQ VHYFEAQAVR
IENRILELQD QGLWSLRQIP RVVEPRRRKC HWDYLLEEAK WLRDDFKGER KWKITMARYY
AKEAARWHHA GEGRWQLQID RKQLGVVPKG IREERRRVAH IEMQDSDMNQ PTPDLVEGCG
SPESDDDFPM DDRHHDTNQG NFAHIYEPPA TLFTLSPEET VFAMPASKAS DDILNQLPLY
GPPEPPTGRH DEVEEEWMKL PVVAISKYAS GKLVIQEEQG PPSKKSRYEY EENQDTYADD
SDEDERLGGG RLIGRSKRDK LRKPSFLPPE QTNVALFKPE YKPLLQRVHN THVPRLPSDF
PPPSFFENRH PSLWLASEDE MLKTLVREYH YNWGLVSQCL TLPGDWHSGS ERRSPWECFE
RWIALEPIPP EFAKSPHFKP IQQRLDVAAR VNGLYGNVPG SAGGSSSGGV KPRRGTAPIR
VEKRRNTRNF MLIESMRKLA KKRETSVNKQ QTNKNQVVAA MKRASESQAS TANPLRTPQY
FSAMKFEREQ KHLEQKNIYS QMQMQQARNG IPPPQARIPH PGQHHALANG VPIPVQQRVG
APAPQGPNGV LQVPRAAPMQ NGTNGLPMRS LPAPLSQGQQ TQRCAPEYFA HLRRITQQHV
IAAPQGYPSS GALGTQGSQP SAQGMQTILQ QAQQAALGQN QQVSVNQQAP QQKCIVPPPI
DSQASVSSPP IPPTPTQLKL ARVLIQEMAA LVQYQNPNRE ATQQTLASYH AQLSQNIQAQ
ARSPVRPSPT RTAADNTGPM IGVNGPVNPA AGPPAVGAIS AGSPRLGNGQ IPTQLPQSQQ
PQANQPLPQP QPAPQQQPI
//
