ID   A0A317T1J3_9PEZI        Unreviewed;       394 AA.
AC   A0A317T1J3;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Di-copper centre-containing protein {ECO:0000313|EMBL:PWW80505.1};
GN   ORFNames=C7212DRAFT_274667 {ECO:0000313|EMBL:PWW80505.1};
OS   Tuber magnatum (white Piedmont truffle).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC   Pezizales; Tuberaceae; Tuber.
OX   NCBI_TaxID=42249 {ECO:0000313|EMBL:PWW80505.1, ECO:0000313|Proteomes:UP000246991};
RN   [1] {ECO:0000313|EMBL:PWW80505.1, ECO:0000313|Proteomes:UP000246991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=091103-1 {ECO:0000313|EMBL:PWW80505.1};
RA   Murat C., Payen T., Noel B., Kuo A., Martin F.M.;
RT   "Genomes of Pezizomycetes fungi and the evolution of truffles.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWW80505.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PYWC01000002; PWW80505.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A317T1J3; -.
DR   STRING; 42249.A0A317T1J3; -.
DR   Proteomes; UP000246991; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000246991};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..394
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016407184"
FT   DOMAIN          279..290
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   394 AA;  44629 MW;  2ABC332ACCCE8A3F CRC64;
     MQLSRLFNFL LFISPLAVCR AVASPHKEVY SSGGGECKNP LVRREWRLLP DHEKKEYIDA
     VKCLQTLPAL TSNAVPGAIT RFDDFQGVHI RQAEIIHNVG FFQHWHRYLL WFYEKALREE
     CGYSGAQPYW DWTLDSTSES AFINSPIWCP TTGFGGNGPY LNVSGNPFLK IPGRTGGGCV
     PDGPFSNYTI HLGPRGSIAK KPQCLRRDFA PSLATLRLTK ELVRLPHCEK NFDWYDFKSQ
     AGAREDGFFV DQASFHSGPH ISVGGEAGHM ADVYASPGDP VFYLHHASVD HEWWKWQNVD
     PETRFKDATG PSIRYDFPFG NHFRGPNITL DFRIGLSELA PAVPLHRVMD TEGDLLCYTY
     AKEKAVYDPT TKKWVAEELS VEEEDWEACK DPEH
//