ID A0A317UPY9_ASPEC Unreviewed; 1030 AA.
AC A0A317UPY9;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=BO83DRAFT_402854 {ECO:0000313|EMBL:PWY63741.1};
OS Aspergillus eucalypticola (strain CBS 122712 / IBT 29274).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1448314 {ECO:0000313|EMBL:PWY63741.1, ECO:0000313|Proteomes:UP000246171};
RN [1] {ECO:0000313|EMBL:PWY63741.1, ECO:0000313|Proteomes:UP000246171}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 122712 {ECO:0000313|EMBL:PWY63741.1,
RC ECO:0000313|Proteomes:UP000246171};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY63741.1}.
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DR EMBL; MSFU01000034; PWY63741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317UPY9; -.
DR VEuPathDB; FungiDB:BO83DRAFT_402854; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000246171; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 105..268
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 345..1028
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 1030 AA; 114712 MW; 5AA05E4BF363182A CRC64;
MEEQVANAIE IAGNPTSDQT LKAQAFDYLN QLRTDPSGWQ VCLTLFTKTP QYSEIIRHVA
LEVVNSAAQA GFIDPQALGY VRDGLMAYLR QVYGQDNVTP DSTSIQNKIA QTITFLFSAL
YGNGWETFFD DLLSLTYKSS ASTSHDNPLG IVFYLRVINA IHEEIGDVLV SRSRAEQDKA
NLLKDLIRSR DMQKIANSWQ QILSEWRDGN DTIVEMSLRA VGSWVSWIDI GLVVNQTMLD
LLFQQLGRAQ KAELREGEEK VRDAAVDVFT EIIGKKMKPE DKMDMILFLN LDTIVTQLSN
SPPLHDNRFT FKYDTDLAET VAKLVNITVI DIVRALEQDT VTADCNAKAT GLLQAFLPHI
LRYFSDEYDE VCSTVIPCVS DLLSYLRKIA KVNPALAEQH SSILLPILKA IIAKMRYDET
SSWGDEDDQT DEAEFQELRK RLGVLQQIVA SVNEQLCMEA VSEVVGNTFE SLRQSGAQLD
WRDLDLALHE MFLFGEVAVR AGSLYNKGVP NNAAAERLVG MMLKMVESDI RSFTHPATQL
QYMEICVRYS SFFQYHTHLI PTVLESFLQL VHHPVKKVKT RSWYLFQRLV KQLRTHVGNV
AQTVVEALGD LLVINAELPT EGSDGDEMSS EDHEGSADAV FNSQLYLFEA VGIICSTPTV
PADKQVLYAQ SVLNPVFMDM EKNLAQAKAN DERALLQIHH DIMALGTLAR GFSDWMPGTS
SPASLPAPEV SEAFMQVSEA TLVALESLKT SFNVRTAARF AFSRLIGVLG SRILPQLPRW
IDGLLTQTSS RDEMALFLRL LDQVIFGFKA EIYSILDALL TPFLQRVFSG IADAPTGTDD
EVQLAELKRE YLNFLLAVLN NELGAVIISE RNQPMFETVI GTIEHFAKDI EDFTTAKMAF
SVLSKMGSSW GGPDIAPEGA NGAAAQQQAL PGFGQFMITR LSPLCWALPA TPSFNSKDAQ
AKQVLAEAGG LQRTIYAKTG MEYLQYLRDR ELPGMGMGAD LVEEFVGALG RLDMKGFRQF
FPSFIQRLSA
//
