ID A0A317UQN4_ASPEC Unreviewed; 1441 AA.
AC A0A317UQN4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ABC multidrug transporter {ECO:0000313|EMBL:PWY62340.1};
GN ORFNames=BO83DRAFT_442136 {ECO:0000313|EMBL:PWY62340.1};
OS Aspergillus eucalypticola (strain CBS 122712 / IBT 29274).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1448314 {ECO:0000313|EMBL:PWY62340.1, ECO:0000313|Proteomes:UP000246171};
RN [1] {ECO:0000313|EMBL:PWY62340.1, ECO:0000313|Proteomes:UP000246171}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 122712 {ECO:0000313|EMBL:PWY62340.1,
RC ECO:0000313|Proteomes:UP000246171};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY62340.1}.
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DR EMBL; MSFU01000046; PWY62340.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:BO83DRAFT_442136; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000246171; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241:SF620; ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE PDR18-RELATED; 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 483..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 619..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 729..746
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1140..1160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1172..1195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1215..1243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1255..1275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1281..1301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1308..1326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1408..1427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..370
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 806..1049
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1441 AA; 161456 MW; CF50B46F0129E570 CRC64;
MDPPHRDGAD ENDLSLQLTK TQTASSVVTN EQRRALTNIA SELHTESLAA VITNEKVLDP
SHPQFDPYQW AKVTIRALDA EDIDARQQGI LFEDLSVHGS GSSLHLQQTV LSTLMSPFKL
ATSAFRSKKS TRRTILHSHD GLLESGELLL VLGRPGSGCS TFLKTISGHL HGLELDPQSN
VQYKGIAFSQ MIKEYRGEVL YNQEVDKHFP HLTVGETLEF AAHARAPHNR IGGMSRAEYV
KTRVQVIMAF FGISHTYNTK VGNDFIRGVS GGERKRVSIA EMALSRAPIG AWDNSTRGLD
AAMALEIIQA LRLSSDLVGS CHAVAAYQTS ESMYQLFDQV VVLYEGRQIY YGPQQEAAQY
FEEMGWERPL KQITPDFLTS ITNPRERIAR KDMADRVPRT PAEFEAYWKK SPQYQALKAK
MHSYKARYAP GVELEKRFGE SKQAQQAKHV RPKSPYLLSI PMQIRICLRR AYQRTRNDLP
TTLITVFVQI ALSLIIGSIF YNTPAATAGF FQRGATLYFS VLMNALITIN EIMSLYAQRP
VVEKQAGYAF VHPFAEALAS IILDFPIKLF RCICFSIILY FMANLRREPS QFFIYILFLI
TTIVTMSGVF RSLGSATKSI GQAMALAGIC VICMVVYTGF TLPQPYMHPW FSWIRWINPI
FYSFEGLVAN EFHGRNFECS EFIPSYPSLS GDSFICSAVG AVAGARTVSG DQFISLNYEY
SYSHIWRNYG ILIAFLVFFN ALYLTITELS PGAKPTAEAL VFRPGHVPAN LQNDEETGVE
SVQAVTEGAG ESDLGAAEIP EQKEIFTWKN LSYDIPVKEG TRRLLDEVSG FVKPGTLTAL
MGVSGAGKTT LLDVLAQRAS LGVITGELFV NGKDLNASFP RKVGYVQQQD MHLAQSTVRE
ALRFSAVLRQ PKTVSLQEKY AYVEEVIKML DMEDFAEAVV GNPGNGLNVC QRKLLSIGVE
LAAKPELLIF LDEPTSGLDS QSAWAICTFM RKLAHHGQAV LATIHQPSAL LFEHFDRLLF
LAKGGKTVYF GDIGQQSQTL LNYFQSNGAR RCEATENPAE YMLDIIGAGA SGKSTIDWVQ
TWNNSPERKE LHAELDRICQ KGASLPSRDE TIAEFAMPLS SQFYYVTQRV FQQYYRQPEY
VLAKFVLGIV SGLFIGFSFW QSDDSQQGFQ NVLFSLFLLC TIFTTLVNQI MPHFVANRAL
YEVRERPSKV YSWKIFIIAQ FLAEIPWHIV LAVCAWASFY FAVFGADQSS DRMGLILLFV
IQFYIFASSF AQFIISALPD PALGGMLAVF MFGLSLIFNG VMQPPSALPG FWIFMWRVSP
LSYYIAGISS TALHGRPIVC SDSELSVFNP PSGQTCGEYL ADYLTTATGR LYNENATESC
EYCSLRSADQ YLAGREISWD DRWRDYGIFW AYFVFNICAA IVLYYVFRVR PYNKKTKAKR
A
//
