ID   A0A317VE58_9EURO        Unreviewed;      1032 AA.
AC   A0A317VE58;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Acetyl-CoA synthetase-like protein {ECO:0000313|EMBL:PWY71719.1};
GN   ORFNames=BO70DRAFT_342808 {ECO:0000313|EMBL:PWY71719.1};
OS   Aspergillus heteromorphus CBS 117.55.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448321 {ECO:0000313|EMBL:PWY71719.1, ECO:0000313|Proteomes:UP000247233};
RN   [1] {ECO:0000313|EMBL:PWY71719.1, ECO:0000313|Proteomes:UP000247233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 117.55 {ECO:0000313|EMBL:PWY71719.1,
RC   ECO:0000313|Proteomes:UP000247233};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWY71719.1}.
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DR   EMBL; MSFL01000027; PWY71719.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A317VE58; -.
DR   STRING; 1448321.A0A317VE58; -.
DR   VEuPathDB; FungiDB:BO70DRAFT_342808; -.
DR   OrthoDB; 2327998at2759; -.
DR   Proteomes; UP000247233; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43439:SF2; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   PANTHER; PTHR43439; PHENYLACETATE-COENZYME A LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000247233}.
FT   DOMAIN          21..346
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          728..908
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
SQ   SEQUENCE   1032 AA;  114630 MW;  A6EA9007EE1E1C81 CRC64;
     MESSNTYEAA GKRLLVSHID RVAALEPLRP AVHQLTPGQP EATVQHLTFR DLANLVNQLA
     WWLDGLVTKG STIAYLAPSD LRHALLCLAG VKVGVKVLLL SPRNSTEVNE HLLRVTECGT
     ILFDGTFEAA VSHLETQPLE AIPVPELLEL LRTQTPVNEY RYTDTLDAVE GEGFAIVHTS
     GSTGLPKPVT ITHGALASQD AHRNLSSTEN LGQKLQLELI AEAKRPYISF PLFHIAGLFF
     SCYLLFSRSS LVFGYPNRPP SCQILKDVLR LANADAAFLP PLIVDQIPQD PDLMDLISSD
     VNFVVTGGGP VSHESGSIVS QKTSLQGVMG SSETLSLAQF VTEPENWHCF HFSKDLCGIE
     WRPTRNTPRG IEGPDEEIYE MVLQRSDEFG QYQSIFKNFP HIREYPTKDL YRKHPTIPDH
     WECKGRADDI IVLSTGEKLN PTNMELKISA LPHVTGAVVM GRQRPHPVLL LELATCIDIS
     SDESVVNEIV SMVQSINRES SRDAQINKDD VIFAKAEKPF IRTSKGSVHR KQTEDLYSQE
     VDSHYKSADY SRERLPVTFD TTNRETLENT LIQLVSGLTS VNNMRPHDDF FKCGLDSKQA
     QIVAASIQNL LKEKHQEFSS PADAIYSYPN AYGLSGYVLQ ELNQGRVRDS SEVFEATFKR
     FRKLLPQSLA TIKSDKKSQR DHVLLTGSTG FIGSFLLDTL VKRDNVSQIT CLDRSLVKGD
     PPFGCSVQRL QGDLSKPLLG LPQDTYSQLL QSVTKIVHCQ WAVNFNWPLH LFESNIRGVV
     NLINLSLKAN YTTPIVFISS VASVAKWDQL QPVPESHLAS PSYALTGYGQ SKLIASLLLH
     HAGHELGMPS IICRVGQVGG PIHKDGVWPQ RDWFPTLLRA SKAIGYLPSS LGDSSDLNWI
     PVDILAEILA DPALLDWQNQ ATSYCNLVNP LIKDYKDILP TIAQRLEPVC KVVPFSKWVR
     VLETSSIEAQ AKGAPIPPGV ELLAFYQYLA SQSKGSSVRL STEVTETRIP LLHSMGAVNR
     AWMETWMDQW GF
//