ID   A0A317VTA4_ASPEC        Unreviewed;       665 AA.
AC   A0A317VTA4;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Cysteine proteinase {ECO:0000313|EMBL:PWY77553.1};
GN   ORFNames=BO83DRAFT_219997 {ECO:0000313|EMBL:PWY77553.1};
OS   Aspergillus eucalypticola (strain CBS 122712 / IBT 29274).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448314 {ECO:0000313|EMBL:PWY77553.1, ECO:0000313|Proteomes:UP000246171};
RN   [1] {ECO:0000313|EMBL:PWY77553.1, ECO:0000313|Proteomes:UP000246171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 122712 {ECO:0000313|EMBL:PWY77553.1,
RC   ECO:0000313|Proteomes:UP000246171};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWY77553.1}.
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DR   EMBL; MSFU01000007; PWY77553.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A317VTA4; -.
DR   VEuPathDB; FungiDB:BO83DRAFT_219997; -.
DR   OrthoDB; 1749511at2759; -.
DR   Proteomes; UP000246171; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   CDD; cd02662; Peptidase_C19F; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR24006:SF936; C-TERMINAL HYDROLASE, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   Pfam; PF00443; UCH; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        36..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          144..592
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
FT   REGION          254..284
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          369..389
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          600..665
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        262..284
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        611..653
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   665 AA;  73272 MW;  52AA7F821DCB0E81 CRC64;
     MNARREGINF LTPNPFNVQR SNYETVLQQL QGNPSLVASI LVTLITLYFT ISYWGPASLS
     VARIAWNILV HLTPSRLIAA LDSQTRKSDT TDENPLSMTF EAKSEAMQRI LGLDDTSFSS
     LFPRAPAFSS FGTSLLSSKN NVPPGLGNWD NSCYQNSIIQ GLASLQSLEK FLDQNVEQLG
     EKALMSTHQA LKDIIERLNS ADSNGQRLWT PADLKSMSSW QQQDAQEYFS KIVDQLDLEV
     QQATRRHTRN LGLKMAGPQE HVIGSGSSQE LQENSGAESR STGNQVFRNP LEGLLAQRVG
     CIQCGWTEGL SLIPFNCLTV PLGPKFEYDI RECLHHYMHL EPIEGVECAK CTLLRVQSQL
     LNLLKQISDD EETPSATPES PKISDALRSS AQERLQAVEQ ALGEEDFAEK TLSQKCHIPG
     KNRVSTTKSR QAVVARPPQC LVIHINRSMF DETTGMLRKN YAAVKFPNTL NLNPWCLGGV
     SKNGEPNLEA WETNPSVSML SHAGRGATAG GHYQLRAVIT HYGRHENGHY ICYRKYPTDS
     FPAHVPDAII EADGDKERDE RWYRLSDEDV QMVSEASVMS QGGAFMLFYE AVDDYSPEAA
     EDVDSGLAEE EGSAPSSSCT PSETMSTTSA ATGDSTSDVS QATSVSTALN VEPRSEKSLL
     MSDVD
//