ID A0A317VUA1_9EURO Unreviewed; 1095 AA.
AC A0A317VUA1;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Importin beta-3 subunit {ECO:0000313|EMBL:PWY76428.1};
GN ORFNames=BO94DRAFT_473321 {ECO:0000313|EMBL:PWY76428.1};
OS Aspergillus sclerotioniger CBS 115572.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1450535 {ECO:0000313|EMBL:PWY76428.1, ECO:0000313|Proteomes:UP000246702};
RN [1] {ECO:0000313|EMBL:PWY76428.1, ECO:0000313|Proteomes:UP000246702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115572 {ECO:0000313|EMBL:PWY76428.1,
RC ECO:0000313|Proteomes:UP000246702};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC {ECO:0000256|ARBA:ARBA00009340}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY76428.1}.
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DR EMBL; MSFK01000027; PWY76428.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A317VUA1; -.
DR STRING; 1450535.A0A317VUA1; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000246702; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR040928; Importin_rep_5.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR024687; MMS19_C.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18816; Importin_rep_5; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR Pfam; PF12460; MMS19_C; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000246702};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 30..111
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1095 AA; 121139 MW; 8EF95D8A46373ADD CRC64;
MSLLPPEVHS ALSQLLRALS TPDNTIRAQA EEQLNNDWIQ GRPDVLLMGL AEQIQGAEDV
LTRSFSAVLF RRIATKTRKD PVSNEAKELF STLTGEQRLI IRQKLVTCLT NESVTDTRKK
IGDAVAEIAR QYTDNGDQWP ELLGVLFQAS QSPDAGLREA AFRIFNTTPG IIEKPHEEAV
VGVFSKGFKD DVVSVRIAAM EAFASFFRSI AKKSQTKFFS LMPDLLNILP PLKESTESDE
LSSAFLSLIE LAEICPKMFK SMFNNLVTFS ISVIADKDLS DQVRQNSLEL MATFADYAPS
MCKKNSEFAQ QMVTQCLSLM TDIGVDDEDA SEWNASEDLD LEESDLNHVA GEQCMDRLAN
KLGGQIILPA TFAWIPRMMS SSAWRDRHAA LMAISAISEG CRDLMVGELD QVLRLVVPAL
QDPHPRVRYA GCNALGQMST DFAGTMQEKY HAVVLTNIIP VLNSTEPRVQ AHAAAALVNF
CEEAERKVLE PYLGDLLQHL LLLLRSPKRY VQEQALSTIA TIADSAENAF EQYYDTLMPL
LFNVLKEEQS KEYRLLRAKA MECATLIALA VGKEKMGQDA LNLVQLLGNI QQNIVDADDP
QSQYLLHCWG RMCRVLGQDF VPYLPGVMPP LLTVAAAKAD IQLLDDEDQI DQVEQDEGWE
LVPLKGKIIG IKTSALEDKN TAIELITIYA QILEAAFEPY VLETMEKIAV PGLAFFFHDP
VRVSSAKLIP QLLNSYKKAH GDQSAGFAGI WNKVAEKIIE VLSAEPTVDT LAEMYQCFYE
SVEVVGQNCL SQQHMQAFIE SAKSTLEDYQ LRVKARLEDR AEADDGEDDN LDYEYAVEDD
QNLLSDMNKA FHTIFKNQGT TFLPAWEQLM AFYDAFISSQ DPTQRQWALC IMDDVLEFCG
PESWNYKDHI MQPLAAGLQD PNAANRQAAA YGVGVAAQKG GAAWGDFVAA SIPSLFQVTQ
INQARSEEHV FATENASASI AKILHYNASK VQNATEIVAN WIGTLPITFD EEAAPYAYSF
LAQLIDQQNP VVLSNADKVF GHIVAALEAE TLQGQTAARV ATSAKQLVAA TGLNAEQILA
GVNPDNQAAV RSYFQ
//
