ID A0A317W6N4_9EURO Unreviewed; 1938 AA.
AC A0A317W6N4;
DT 10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
GN ORFNames=BO94DRAFT_548214 {ECO:0000313|EMBL:PWY80927.1};
OS Aspergillus sclerotioniger CBS 115572.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1450535 {ECO:0000313|EMBL:PWY80927.1, ECO:0000313|Proteomes:UP000246702};
RN [1] {ECO:0000313|EMBL:PWY80927.1, ECO:0000313|Proteomes:UP000246702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115572 {ECO:0000313|EMBL:PWY80927.1,
RC ECO:0000313|Proteomes:UP000246702};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the initiation of assembly of the COPII coat
CC required for the formation of transport vesicles from the endoplasmic
CC reticulum (ER) and the selection of cargo molecules. Also involved in
CC autophagy. {ECO:0000256|ARBA:ARBA00024687,
CC ECO:0000256|RuleBase:RU364101}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWY80927.1}.
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DR EMBL; MSFK01000021; PWY80927.1; -; Genomic_DNA.
DR STRING; 1450535.A0A317W6N4; -.
DR OrthoDB; 1361743at2759; -.
DR Proteomes; UP000246702; Unassembled WGS sequence.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09233; ACE1-Sec16-like; 1.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR InterPro; IPR024468; Sec16_N.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR PANTHER; PTHR13402:SF6; SECRETORY 16, ISOFORM I; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
DR Pfam; PF12935; Sec16_N; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|RuleBase:RU364101};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101}; Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000246702};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 302..525
FT /note="Sec16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12935"
FT DOMAIN 999..1116
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 1175..1476
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 51..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1143..1168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1523..1786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1798..1938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..87
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..633
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..701
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..744
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..777
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..933
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1143..1161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1523..1605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1646..1660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1694..1746
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1833..1871
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1938 AA; 205941 MW; F79899B02F907F13 CRC64;
MESGAQIRRQ CHPVPTGPTP LEIDTAIEAT TIPLGSPMET PHELTISDIA FPDPDTAVPP
QEAAIPDMTD SYSLPNPGQV ATHDEVPETS SDGTEAMPEV TYDQSYPILD ESQTEHGHDK
DVPLGDTDGH ITEVQPIQHQ EEEENPPVET IHAQPLDAES GHDKDVPMDD TEDQVEEVQP
IQHQEATDAP VMNTEHGHDD ALVDGTEGQV VESQPQEDEL PPTETTDVQA LDAEPGHGED
VLINSTGQVV EVEPPQDEGQ SLPTETIETQ ALDAEEGNTT HTSEQDEYEP ADTNGEAENN
DDIWGGPANE DAAEDDFFNQ LKTQTKPIYV PAETESRFEE GVPLLDDTPE SPAKPTAPEE
SQIDNFFAGD EDEEDGFFKT VQSSAPPEES EAPSHITRKS TFQVMDSLGV SPDSPMSDAD
PAAQEFDSVL AAAASENNVK KSSSEEDLAA RWEAELSEEP VVAAPTEDDL AARWQMELDD
DDDLLLEDEV AEAPAVDQGP ALQNINGAPP SLSSPFGTPQ ISTAAYTPHQ PSTSDLLHGI
PLPGAAPPAN IAASADYFAR QPPPSAGANK AESFAERAKE GYRSPYDLPE DLTRSRRPVA
SHKPVVTQPG STPPPPRSNS IPVPPPNPST VSAPRMSTPP AGTSSTATMA APKNFYEELP
LPPPRTQSRQ ASSGRYTPGA NAAPAATSHP PPPPANPYAS LPVATPPAVD AYTPPPIQQP
ERLDSYGSLS ALSAPSGSSA PPVTSRYSPK PPTVQAGIKP PPSPRYSPAP PPAVTAPPTR
NRYASQPSIP PIQGTALPFQ PRTSSPLAYH EKVSYRSHEN LDQQLSMEPP ASIPPIEVQE
QPSGPAVNSP TVSSGFAFGP ETVSGDASAH QMSQQPMSPP RNQYAPPDYV DEFSKRVAPI
GSVPPAPVAP AEDSPFVPPR RSLTQSPGQQ ALGPRLSVPT VDPLQRPASV HGSGSPIKAV
NPYAPVQVSA HNRVASQPLD FIPPTDDQQF DPLERWKGAP IVKFGFGGAI LSCSPKHIPR
YSAGQATPKI KSSPGEVKIH QLSDWISTPD TIVRHPGPLK SKSKKKDLLA WLSSKIAAFE
NEGIPESSRL HPDSQKRNDE KILLWKVVRV LVEHDGVLEG SPDVQKSLRQ IIFPHLQDGD
SEQTYGGSLP SFNTSQPLDS PSRPDAVDPQ AIENVRNNLL LGEREKAVWG AVDHRLWGHA
MIIASTMDKP VWKQVVQEFV RREVRSASGN TESLAALYEI FAGNVEESVD ELVPPSARAG
LQMVSKVNGQ GPPKNALDGL DSWRDTLGLV LSNRSPEDHQ ALLALGRLLS SYGRIEAAHI
CFIFSRAAVF GGVDDPQASV VLLGADHQHM SSAALQDDNS ILLTEAYEYA TSVLSASPKP
VLPHLLAFKL VHACSLADQG RKSEAQQYCD AIAATLKATT KPSTYHHQHL YFGVDELSAR
LRQTTSDGGS SWISRPSMEK VSGSMWAKFN SFVAGEDNEA ASAGSTKAGD GDIGPFAKIA
GTPTVSRSPS MSDIYAPYAA QPNYSSGPSR YQPNNQYAPT SSPEQLRGRS SLDSQRSSSY
GFGYGQRRGS QEPSTPVESN MYQGGMPFNS PPATGYQSTP PQTSYMPLAP VKEDLAPQSH
ADASSAPVQE AFGSGSPYQP PGYGSFGQPF MNQPSETAPT SDAGGYMPPT GSGGYEAPSG
ESHVEPATAM PEESNDEEPP KKKSFMDDDD EDDLAARAAA IQKAEKARKD READEAFRKA
AEADAQKPAP AKKGWFGGWF GGAAGSGKKE GEISNKPIRA KLGEENSFYY DTDLKKWVNK
KDPGSATAAR ATPPPPRASA PPSRTASGSS AAPPPPASGP SPMLSGPGSR PPSTTGVPPH
PGSPGPSSLG LPPPSIQRSV STGAAMPTPP IGLAAPPRPA TSLSNASSID DLLGAPQARK
GPAARGKKKG RYVDVMAK
//
