ID   A0A317W8K7_9EURO        Unreviewed;      1019 AA.
AC   A0A317W8K7;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Acetyl-CoA synthetase-like protein {ECO:0000313|EMBL:PWY82061.1};
GN   ORFNames=BO70DRAFT_429155 {ECO:0000313|EMBL:PWY82061.1};
OS   Aspergillus heteromorphus CBS 117.55.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1448321 {ECO:0000313|EMBL:PWY82061.1, ECO:0000313|Proteomes:UP000247233};
RN   [1] {ECO:0000313|EMBL:PWY82061.1, ECO:0000313|Proteomes:UP000247233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 117.55 {ECO:0000313|EMBL:PWY82061.1,
RC   ECO:0000313|Proteomes:UP000247233};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De Vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWY82061.1}.
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DR   EMBL; MSFL01000012; PWY82061.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A317W8K7; -.
DR   STRING; 1448321.A0A317W8K7; -.
DR   VEuPathDB; FungiDB:BO70DRAFT_429155; -.
DR   OrthoDB; 2230730at2759; -.
DR   Proteomes; UP000247233; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43439:SF2; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   PANTHER; PTHR43439; PHENYLACETATE-COENZYME A LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000247233}.
FT   DOMAIN          28..337
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          630..867
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
FT   REGION          453..502
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          876..895
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        461..476
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1019 AA;  110150 MW;  450956A633547551 CRC64;
     MANIDPRGVL FPAYVDQVAE AQPEAIYAEF PNHPLSYDYG FRKITYRDLA NAINGVAKWL
     IETLGPGQDE VLAYFGPTDV RYPALVFGAL KAGYVMYLPS PRNSPAAHRH LLQTLNCTKL
     LVTTPRPPPV AGIIAAAPLD VFELPGVNDL LGTTHPHIPF TKTYPAAADE RCVIVHTSGS
     TGIPKPIIWT HESIMRYYNM AGLAAPEGDF NQCDLTQGKR QFLCLPAFHS GGLASLSFMA
     VPSGMTSVCP ISGIPTAAGM VAALKKTPFD VALVPPSVIL ELAAAPDLLD YVSQHMSHLG
     YCGGDLPQAV GELVASRIPL INHYGASEMG MLHLIQSPHR DPLTDWGYVQ VHPGLGIEFR
     PTTATESELV MVHRPELTSF QMPPTIFPGI EEYHSQDLFV RHPDPAKADL WRWSARLDDI
     ITFLNGEKTN PISMEQHIVA SNPDVSVALP SPEPPAARRR HRAAVAQHRG RQRRVPGPRP
     HHQDAHPVHQ PGQALPRSGK GTAQRAATLA LYAPELDALY ADADTLTVRD GPSTGPGPVD
     DPAAISAFIE TSLLAVTGWT PDALSAESFF HSGLDSLQIL TLSRTLRNGL QLPEIIPNLI
     YRHPNCNPNS NPPLLLLLLP SPSQPQTIIL TGSTGTLGSY LLAALLNNPN ISHIHCLNRN
     PSACSIQQSQ ALKFHLPALS PSDPRLTFHT TDLTRPDLGL SPSTLQTLRT TTTTLIHNAW
     TVNWLLPLQF FKPLLTATLN LLNFCADAPS SPHFFFLSTV GSVTPSTSPS IPEQIVTTTL
     PAANAYSNSK YIAEHLIASA TARSPSLRAS IARVGQVAGA VRAPGLWSRT EWFPSLVRSA
     AHLRALPDSL GPMSNLDWVP IDLLADVLVE LAVSPVPSAE EEEEEEEGSE GKGNLNVYHP
     HNTHKVQWTT LLPTIASALP DPESSSSPME TIPLAEWRAR VAADVAKTAG DAPDNLQIVL
     ERNPAAKLAD FWSVLEGVGA EGSVMVFETE RTQRVSGLLG GVEGVKGGWV EKWVGEWFA
//